[HTML][HTML] Tumorigenicity assessment of cell therapy products: The need for global consensus and points to consider
Y Sato, H Bando, M Di Piazza, G Gowing, C Herberts… - Cytotherapy, 2019 - Elsevier
Pluripotent stem cells offer the potential for an unlimited source for cell therapy products.
However, there is concern regarding the tumorigenicity of these products in humans, mainly …
However, there is concern regarding the tumorigenicity of these products in humans, mainly …
Current standards and pitfalls associated with the transfection of primary fibroblast cells
M Kucharski, P Mrowiec, E Ocłoń - Biotechnology Progress, 2021 - Wiley Online Library
Cultured fibroblast cells, especially dermal cells, are used for various types of scientific
research, particularly within the medical field. Desirable features of the cells include their …
research, particularly within the medical field. Desirable features of the cells include their …
Patient-derived fibroblasts with presenilin-1 mutations, that model aspects of Alzheimer's disease pathology, constitute a potential object for early diagnosis
G Lopez-Toledo, MC Silva-Lucero… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD), a neurodegenerative disorder that can occur in middle or old age,
is characterized by memory loss, a continuous decline in thinking, behavioral and social …
is characterized by memory loss, a continuous decline in thinking, behavioral and social …
Evaluating the potential of poly (beta-amino ester) nanoparticles for reprogramming human fibroblasts to become induced pluripotent stem cells
Background Gene delivery can potentially be used as a therapeutic for treating genetic
diseases, including neurodegenerative diseases, as well as an enabling technology for …
diseases, including neurodegenerative diseases, as well as an enabling technology for …
Biocompatibility of graphene oxide nanosheets functionalized with various amino acids towards mesenchymal stem cells
Graphene and its derivatives have gained popularity due to their numerous applications in
various fields, such as biomedicine. Recent reports have revealed the severe toxic effects of …
various fields, such as biomedicine. Recent reports have revealed the severe toxic effects of …
[HTML][HTML] The study of apoptosis-inducing effects of three pre-apoptotic factors by gallic acid, using simulation analysis and the comet assay technique on the prostatic …
J Saffari-Chaleshtori, E Heidari-Sureshjani… - … Malaysian Journal of …, 2017 - ncbi.nlm.nih.gov
Background In this study, we demonstrated the effects of the Gallic Acid (GA) molecule on
the prostate cancer cells line PC3 using the comet assay (Alkaline electrophoresis) …
the prostate cancer cells line PC3 using the comet assay (Alkaline electrophoresis) …
[HTML][HTML] The effects of thymoquinone on viability, and anti-apoptotic factors (BCL-XL, BCL-2, MCL-1) in prostate cancer (PC3) cells: an in vitro and computer-simulated …
J Saffari_Chaleshtori, E Heidari-Sureshjani… - Advanced …, 2019 - ncbi.nlm.nih.gov
Purpose: Since active plant ingredients can induce apoptosis in many tumors, in this study
we evaluate the apoptotic effects of thymoquinone (TQ) on PC3 cells. Also, we predicted the …
we evaluate the apoptotic effects of thymoquinone (TQ) on PC3 cells. Also, we predicted the …
Inhibitory effects of bilirubin on colonization and migration of A431 and SK-MEL-3 skin cancer cells compared with human dermal fibroblasts (HDF)
This study evaluated the inhibitory effects of bilirubin on colony formation and cell migration
of melanoma and non-melanoma skin cancer cell lines SK-MEL-3 and A431, compared with …
of melanoma and non-melanoma skin cancer cell lines SK-MEL-3 and A431, compared with …
Expression changes of SIRT1 and FOXO3a significantly correlate with oxidative stress resistance genes in AML patients
S Mizani, A Keshavarz, N Vazifeh Shiran… - Indian Journal of …, 2023 - Springer
The increased metabolism in acute myeloid leukemia (AML) malignant cells resulted in the
production of high levels of free radicals, called oxidative stress conditions. To avoid this …
production of high levels of free radicals, called oxidative stress conditions. To avoid this …
The protective effect of oleuropein against radiation-induced cytotoxicity, apoptosis, and genetic damage in cultured human lymphocytes
F Amani, M Allahbakhshian Farsani… - … Journal of Radiation …, 2021 - Taylor & Francis
Purpose The aim of this study was to evaluate the effects of oleuropein radiation protection
and to find an effective radioprotector. Materials and Method Human mononuclear cells …
and to find an effective radioprotector. Materials and Method Human mononuclear cells …