Collagen: quantification, biomechanics and role of minor subtypes in cartilage
BJ Bielajew, JC Hu, KA Athanasiou - Nature Reviews Materials, 2020 - nature.com
Collagen is a ubiquitous biomaterial in vertebrate animals. Although each of its 28 subtypes
contributes to the functions of many different tissues in the body, most studies on collagen or …
contributes to the functions of many different tissues in the body, most studies on collagen or …
The phasor plot: a universal circle to advance fluorescence lifetime analysis and interpretation
The phasor approach to fluorescence lifetime imaging has become a common method to
analyze complicated fluorescence signals from biological samples. The appeal of the …
analyze complicated fluorescence signals from biological samples. The appeal of the …
Biodegradable magnesium alloys promote angio‐osteogenesis to enhance bone repair
Biodegradable metallic materials represent a potential step‐change technology that may
revolutionize the treatment of broken bones. Implants made with biodegradable metals are …
revolutionize the treatment of broken bones. Implants made with biodegradable metals are …
FXR/TGR5 dual agonist prevents progression of nephropathy in diabetes and obesity
Bile acids are ligands for the nuclear hormone receptor farnesoid X receptor (FXR) and the
G protein–coupled receptor TGR5. We have shown that FXR and TGR5 have renoprotective …
G protein–coupled receptor TGR5. We have shown that FXR and TGR5 have renoprotective …
Recapitulating pancreatic tumor microenvironment through synergistic use of patient organoids and organ‐on‐a‐chip vasculature
Tumor progression relies on the interaction between neoplastic epithelial cells and their
surrounding stromal partners. This cell cross‐talk affects stromal development, and …
surrounding stromal partners. This cell cross‐talk affects stromal development, and …
Molecular and tissue alterations of collagens in fibrosis
S Ricard-Blum, G Baffet, N Théret - Matrix Biology, 2018 - Elsevier
The collagen network is altered in fibrotic diseases associated with extracellular matrix
(ECM) biosynthesis and remodeling. This mini-review focuses on the quantitative and …
(ECM) biosynthesis and remodeling. This mini-review focuses on the quantitative and …
[HTML][HTML] Multicolor two-photon imaging of endogenous fluorophores in living tissues by wavelength mixing
Two-photon imaging of endogenous fluorescence can provide physiological and metabolic
information from intact tissues. However, simultaneous imaging of multiple intrinsic …
information from intact tissues. However, simultaneous imaging of multiple intrinsic …
[HTML][HTML] Two-photon autofluorescence lifetime imaging of human skin papillary dermis in vivo: assessment of blood capillaries and structural proteins localization
EA Shirshin, YI Gurfinkel, AV Priezzhev, VV Fadeev… - Scientific reports, 2017 - nature.com
The papillary dermis of human skin is responsible for its biomechanical properties and for
supply of epidermis with chemicals. Dermis is mainly composed of structural protein …
supply of epidermis with chemicals. Dermis is mainly composed of structural protein …
[HTML][HTML] Digital image analysis of picrosirius red staining: A robust method for multi-organ fibrosis quantification and characterization
Current understanding of fibrosis remains incomplete despite the increasing burden of
related diseases. Preclinical models are used to dissect the pathogenesis and dynamics of …
related diseases. Preclinical models are used to dissect the pathogenesis and dynamics of …
Advances in fluorescence microscopy techniques to study kidney function
Fluorescence microscopy, in particular immunofluorescence microscopy, has been used
extensively for the assessment of kidney function and pathology for both research and …
extensively for the assessment of kidney function and pathology for both research and …