Extracellular vesicles as a source of prostate cancer biomarkers in liquid biopsies: a decade of research

M Ramirez-Garrastacho, C Bajo-Santos, A Line… - British journal of …, 2022 - nature.com
Prostate cancer is a global cancer burden and considerable effort has been made through
the years to identify biomarkers for the disease. Approximately a decade ago, the potential of …

Fibrinogen-like protein 1 (FGL1): the next immune checkpoint target

W Qian, M Zhao, R Wang, H Li - Journal of Hematology & Oncology, 2021 - Springer
Immune checkpoint therapy has achieved significant efficacy by blocking inhibitory
pathways to release the function of T lymphocytes. In the clinic, anti-programmed cell death …

Imaging-based prediction of molecular therapy targets in NSCLC by radiogenomics and AI approaches: a systematic review

G Ninatti, M Kirienko, E Neri, M Sollini, A Chiti - Diagnostics, 2020 - mdpi.com
The objective of this systematic review was to analyze the current state of the art of imaging-
derived biomarkers predictive of genetic alterations and immunotherapy targets in lung …

Biomarkers in lung cancer

CR Sears, PJ Mazzone - Clinics in Chest Medicine, 2020 - chestmed.theclinics.com
Lung cancer is diagnosed in more than 1.8 million people yearly and remains the leading
cause of cancer deaths in both developing and developed countries, with survival at 5 years …

Accelerating the development and validation of liquid biopsy for early cancer screening and treatment tailoring

D Horgan, T Čufer, F Gatto, I Lugowska, D Verbanac… - Healthcare, 2022 - mdpi.com
Liquid biopsy (LB) is a minimally invasive method which aims to detect circulating tumor-
derived components in body fluids. It provides an alternative to current cancer screening …

Recommendations for the equitable and widespread implementation of liquid biopsy for cancer care

PG Febbo, M Allo, EB Alme, G Cuyun Carter… - JCO Precision …, 2024 - ascopubs.org
Liquid biopsies—tests that detect circulating tumor cellular components in the bloodstream—
have the potential to transform cancer by reducing health inequities in screening …

Comparison of circulating cell-free DNA extraction methods for downstream analysis in cancer patients

P van der Leest, PA Boonstra, A Ter Elst… - Cancers, 2020 - mdpi.com
Circulating cell-free DNA (ccfDNA) may contain DNA originating from the tumor in plasma of
cancer patients (ctDNA) and enables noninvasive cancer diagnosis, treatment predictive …

The economic value of liquid biopsy for genomic profiling in advanced non-small cell lung cancer

DA Ezeife, E Spackman, RA Juergens… - … in medical oncology, 2022 - journals.sagepub.com
Background: Liquid biopsy (LB) can detect actionable genomic alterations in plasma
circulating tumor circulating tumor DNA beyond tissue testing (TT) alone in advanced non …

Evolving trends in lung cancer: epidemiology, diagnosis, and management

R Deshpand, M Chandra, A Rauthan - Indian Journal of Cancer, 2022 - journals.lww.com
Lung cancer is one of the deadliest cancers globally and accounts for most of the cancer-
related deaths in India. Comprehensive data on lung cancer in India are lacking. This review …

Recent updates on innovative approaches to overcome drug resistance for better outcomes in cancer

M Sharma, AK Bakshi, N Mittapelly, S Gautam… - Journal of Controlled …, 2022 - Elsevier
The multi-dimensional challenge of drug resistance is one of the pivotal hindrances for
cancer chemotherapy. A reductive approach to define and distinguish the main aspects of …