Depression is one of the most common comorbidities of many chronic medical diseases
including cancer and cardiovascular, metabolic, inflammatory and neurological disorders …

There is increasing academic and clinical interest in how “lifestyle factors” traditionally
associated with physical health may also relate to mental health and psychological well …

Frailty and depression were linked in observational studies, but the causality remains
ambiguous. We intended to explore it using Mendelian randomization (MR). We obtained …

Background The poor physical health of people with mental illness is a multifaceted,
transdiagnostic, and global problem. People with mental illness have an increased risk of …

Background Evidence of an association between sleep duration and depression was
inconsistent. Methods Adults who participated in the National Health and Nutrition …

The governmental lockdowns related to the COVID-19 pandemic have forced people to
change their behavior in many ways including changes in exercise. We used the brief …

The observational association between gut microbiome and systemic lupus erythematosus
(SLE) has been well documented. However, whether the association is causal remains …

This is a cross-sectional study evaluating the associations of self-reported moderate to
vigorous physical activity, and sedentary behavior with depressive, anxiety, and co …

Objective: Loneliness and physical activity are important targets for research into the impact
of COVID-19 because they have established links with mental health, could be exacerbated …

Exercise has been shown to benefit brain structure and function, particularly in aging
populations. However, the mechanisms by which exercise exerts its effects, especially in …