[HTML][HTML] The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease

J Budni, T Bellettini-Santos, F Mina, ML Garcez… - Aging and …, 2015 - ncbi.nlm.nih.gov
Aging is a normal physiological process accompanied by cognitive decline. This aging
process has been the primary risk factor for development of aging-related diseases such as …

Neurotrophin signalling: novel insights into mechanisms and pathophysiology

M Mitre, A Mariga, MV Chao - Clinical science, 2017 - portlandpress.com
Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are prominent regulators
of neuronal survival, growth and differentiation during development. While trophic factors are …

Neurotrophins and their receptors: a convergence point for many signalling pathways

MV Chao - Nature Reviews Neuroscience, 2003 - nature.com
The neurotrophins are a family of proteins that are essential for the development of the
vertebrate nervous system. Each neurotrophin can signal through two different types of cell …

Trk receptors: roles in neuronal signal transduction

EJ Huang, LF Reichardt - Annual review of biochemistry, 2003 - annualreviews.org
▪ Abstract Trk receptors are a family of three receptor tyrosine kinases, each of which can be
activated by one or more of four neurotrophins—nerve growth factor (NGF), brain-derived …

Neurotrophin-regulated signalling pathways

LF Reichardt - … Transactions of the Royal Society B …, 2006 - royalsocietypublishing.org
Neurotrophins are a family of closely related proteins that were identified initially as survival
factors for sensory and sympathetic neurons, and have since been shown to control many …

[HTML][HTML] Brain-derived neurotrophic factor

DK Binder, HE Scharfman - Growth factors (Chur, Switzerland), 2004 - ncbi.nlm.nih.gov
Nerve growth factor (NGF) was discovered in the early 1950s due to its trophic (survival-and
growth-promoting) effects on sensory and sympathetic neurons (Levi-Montalcini and …

Neurotrophic factors: an overview

SD Skaper - Neurotrophic Factors: Methods and Protocols, 2018 - Springer
The neurotrophins are a family of closely related proteins that were first identified as survival
factors for sympathetic and sensory neurons and have since been shown to control a …

The neurotrophin family of neurotrophic factors: an overview

SD Skaper - Neurotrophic factors: Methods and protocols, 2012 - Springer
The neurotrophins are a family of closely related proteins that were first identified as survival
factors for sympathetic and sensory neurons and have since been shown to control a …

Brain‐derived neurotrophic factor and the development of structural neuronal connectivity

S Cohen‐Cory, AH Kidane, NJ Shirkey… - Developmental …, 2010 - Wiley Online Library
During development, neural networks are established in a highly organized manner, which
persists throughout life. Neurotrophins play crucial roles in the developing nervous system …

Neurotrophic factors in Alzheimer's and Parkinson's diseases: implications for pathogenesis and therapy

TB Sampaio, AS Savall, MEZ Gutierrez… - Neural regeneration …, 2017 - journals.lww.com
Neurotrophic factors comprise essential secreted proteins that have several functions in
neural and non-neural tissues, mediating the development, survival and maintenance of …