The contribution of astrocytes to the neuroinflammatory response in multiple sclerosis and experimental autoimmune encephalomyelitis

R Brambilla - Acta neuropathologica, 2019 - Springer
Neuroinflammation is the coordinated response of the central nervous system (CNS) to
threats to its integrity posed by a variety of conditions, including autoimmunity, pathogens …

A systematic review of resting-state functional MRI connectivity changes and cognitive impairment in multiple sclerosis

D Jandric, A Doshi, R Scott, D Paling, D Rog… - Brain …, 2022 - liebertpub.com
Introduction: Cognitive impairment in multiple sclerosis (MS) is increasingly being
investigated with resting-state functional MRI (rs-fMRI) functional connectivity (FC). However …

Applying multilayer analysis to morphological, structural, and functional brain networks to identify relevant dysfunction patterns

J Casas-Roma, E Martinez-Heras… - Network …, 2022 - direct.mit.edu
In recent years, research on network analysis applied to MRI data has advanced
significantly. However, the majority of the studies are limited to single networks obtained …

Structural and functional connectivity substrates of cognitive impairment in multiple sclerosis

J Zhang, R Cortese, N De Stefano, A Giorgio - Frontiers in neurology, 2021 - frontiersin.org
Cognitive impairment (CI) occurs in 43 to 70% of multiple sclerosis (MS) patients at both
early and later disease stages. Cognitive domains typically involved in MS include attention …

Longitudinal metabolite changes in progressive multiple sclerosis: a study of 3 potential neuroprotective treatments

NA John, BS Solanky, F De Angelis… - Journal of Magnetic …, 2024 - Wiley Online Library
Background 1H‐magnetic resonance spectroscopy (1H‐MRS) may provide a direct index for
the testing of medicines for neuroprotection and drug mechanisms in multiple sclerosis (MS) …

The cross talk between underlying mechanisms of multiple sclerosis and epilepsy may provide new insights for more efficient therapies

A Rayatpour, S Farhangi, E Verdaguer, J Olloquequi… - Pharmaceuticals, 2021 - mdpi.com
Despite the significant differences in pathological background of neurodegenerative
diseases, epileptic seizures are a comorbidity in many disorders such as Huntington …

[HTML][HTML] Spatial patterns of brain lesions assessed through covariance estimations of lesional voxels in multiple Sclerosis: The SPACE-MS technique

C Tur, F Grussu, F De Angelis, F Prados, B Kanber… - NeuroImage: Clinical, 2022 - Elsevier
Predicting disability in progressive multiple sclerosis (MS) is extremely challenging.
Although there is some evidence that the spatial distribution of white matter (WM) lesions …

[HTML][HTML] Characterization of multiple sclerosis lesions with distinct clinical correlates through quantitative diffusion MRI

E Martínez-Heras, E Solana, F Prados, M Andorrà… - NeuroImage: Clinical, 2020 - Elsevier
Diffusion magnetic resonance imaging can reveal quantitative information about the tissue
changes in multiple sclerosis. The recently developed multi-compartment spherical mean …

Epilepsy in multiple sclerosis as a network disease

MB Vlaicu - Multiple Sclerosis and Related Disorders, 2019 - Elsevier
This is a review paper, essentially a commentary with summary of literature that actualizes
the problem of epilepsy in patients with multiple sclerosis. There is a bidirectional relation …

Diffusion-based structural connectivity patterns of multiple sclerosis phenotypes

E Martinez-Heras, E Solana, F Vivó… - Journal of Neurology …, 2023 - jnnp.bmj.com
Background We aimed to describe the severity of the changes in brain diffusion-based
connectivity as multiple sclerosis (MS) progresses and the microstructural characteristics of …