(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …

It is well-established that the nutritional deficiency or inadequacy can impair immune
functions. Growing evidence suggests that for certain nutrients increased intake above …

Apoptosis or programmed cell death is natural way of removing aged cells from the body.
Most of the anti-cancer therapies trigger apoptosis induction and related cell death networks …

An expanding body of preclinical evidence suggests EGCG, the major catechin found in
green tea (Camellia sinensis), has the potential to impact a variety of human diseases …

Nanomedicine integrates different functional materials to realize the customization of
carriers, aiming at increasing the cancer therapeutic efficacy and reducing the off‐target …

Targeting the ubiquitin-proteasome pathway has emerged as a rational approach in the
treatment of human cancer. Based on positive preclinical and clinical studies, bortezomib …

Pyrogallol‐containing molecules are ubiquitous in the plant kingdom. The chemical
synthesis of these molecules remains challenging. Thus, they are obtained via purification …

Throughout the ages, Nature has catered to the basic needs of humans, not the least of
which is the provision of medicines for the treatment of a wide spectrum of diseases. Plants …

Proteasomes are large, multisubunit proteolytic complexes presenting multiple targets for
therapeutic intervention. The 26S proteasome consists of a 20S proteolytic core and one or …

Extracts of tea, especially green tea, and tea polyphenols have been shown to inhibit the
formation and development of tumours at different organ sites in animal models. There is …