Obesity is among the most common and costly chronic disorders worldwide. Estimates
suggest that in the United States obesity affects one-third of adults, accounts for up to one …

Accumulating evidence suggests that insults occurring during the perinatal period alter the
developmental trajectory of the fetus/offspring leading to long-term detrimental outcomes …

Maternal metabolic homeostasis exerts long-term effects on the offspring's health outcomes.
Here, we demonstrate that maternal high-fat diet (HFD) feeding during lactation predisposes …

Metabolic disorders have seen an increased prevalence in recent years in developed as
well as developing countries. While it is clear lifestyle choices and habits have contributed to …

The health consequences of in utero exposure to maternal obesity on future generations are
concerning because they contribute to increased rates of diabetes, cardiovascular disease …

Significant alterations in maternal nutrition may induce long‐term metabolic consequences
in offspring, in particular obesity and leptin and insulin resistance. Although maternal …

Converging lines of evidence from epidemiological studies and animal models now indicate
that the origins of obesity and related metabolic disorders lie not only in the interaction …

The hypothalamus plays a crucial role in controlling metabolism and energy balance, with
Agouti-related protein (AgRP) neurons and proopiomelanocortin (POMC) neurons being …

Maternal high-fat (HF) diet throughout gestation and suckling has long-term consequences
on the offspring's metabolic phenotype. Here we determine the relative contribution of pre-or …

Individuals exposed to high-fat, high-sugar diets before birth have an increased risk of
obesity in later life. Recent studies have shown that these offspring exhibit increased …