Melanin-concentrating hormone control of sleep–wake behavior
JM Monti, P Torterolo, P Lagos - Sleep medicine reviews, 2013 - Elsevier
The melanin-concentrating hormone (MCH) is a 19 aminoacid peptide found in mammals
predominantly in neurons located in the lateral hypothalamus and incerto-hypothalamic …
predominantly in neurons located in the lateral hypothalamus and incerto-hypothalamic …
The melanin-concentrating hormone as an integrative peptide driving motivated behaviors
GB Diniz, JC Bittencourt - Frontiers in systems neuroscience, 2017 - frontiersin.org
The melanin-concentrating hormone (MCH) is an important peptide implicated in the control
of motivated behaviors. History, however, made this peptide first known for its participation in …
of motivated behaviors. History, however, made this peptide first known for its participation in …
Optogenetic identification of a rapid eye movement sleep modulatory circuit in the hypothalamus
S Jego, SD Glasgow, CG Herrera, M Ekstrand… - Nature …, 2013 - nature.com
Rapid-eye movement (REM) sleep correlates with neuronal activity in the brainstem, basal
forebrain and lateral hypothalamus. Lateral hypothalamus melanin-concentrating hormone …
forebrain and lateral hypothalamus. Lateral hypothalamus melanin-concentrating hormone …
Stimulation of the pontine parabrachial nucleus promotes wakefulness via extra-thalamic forebrain circuit nodes
Human and animal studies have identified an especially critical role for the brainstem
parabrachial (PB) complex in regulating electrocortical (electroencephalogram [EEG]) and …
parabrachial (PB) complex in regulating electrocortical (electroencephalogram [EEG]) and …
Neurons containing orexin or melanin concentrating hormone reciprocally regulate wake and sleep
RR Konadhode, D Pelluru… - Frontiers in systems …, 2015 - frontiersin.org
Neurons containing orexin (hypocretin), or melanin concentrating hormone (MCH) are
intermingled with each other in the perifornical and lateral hypothalamus. Each is a separate …
intermingled with each other in the perifornical and lateral hypothalamus. Each is a separate …
Melanin-concentrating hormone (MCH): role in REM sleep and depression
P Torterolo, C Scorza, P Lagos… - Frontiers in …, 2015 - frontiersin.org
The melanin-concentrating hormone (MCH) is a peptidergic neuromodulator synthesized by
neurons of the lateral sector of the posterior hypothalamus and zona incerta. MCHergic …
neurons of the lateral sector of the posterior hypothalamus and zona incerta. MCHergic …
Melanin-concentrating hormone: a new sleep factor?
P Torterolo, P Lagos, JM Monti - Frontiers in neurology, 2011 - frontiersin.org
Neurons containing the neuropeptide melanin-concentrating hormone (MCH) are mainly
located in the lateral hypothalamus and the incerto-hypothalamic area, and have …
located in the lateral hypothalamus and the incerto-hypothalamic area, and have …
The melanin-concentrating hormone system as a target for the treatment of sleep disorders
LE Potter, CR Burgess - Frontiers in neuroscience, 2022 - frontiersin.org
Given the widespread prevalence of sleep disorders and their impacts on health, it is critical
that researchers continue to identify and evaluate novel avenues of treatment. Recently the …
that researchers continue to identify and evaluate novel avenues of treatment. Recently the …
Microinjection of melanin concentrating hormone into the lateral preoptic area promotes non-REM sleep in the rat
L Benedetto, Z Rodriguez-Servetti, P Lagos… - Peptides, 2013 - Elsevier
The ventrolateral preoptic area (VLPO) has been recognized as one of the key structures
responsible for the generation of non-REM (NREM) sleep. The melanin-concentrating …
responsible for the generation of non-REM (NREM) sleep. The melanin-concentrating …
Neurobiology of cataplexy
Cataplexy is the pathognomonic and the most striking symptom of narcolepsy. It has
originally been, and still is now, widely considered as an abnormal manifestation of rapid …
originally been, and still is now, widely considered as an abnormal manifestation of rapid …