Early-life interactions between the microbiota and immune system: impact on immune system development and atopic disease

K Donald, BB Finlay - Nature Reviews Immunology, 2023 - nature.com
Prenatal and early postnatal life represent key periods of immune system development. In
addition to genetics and host biology, environment has a large and irreversible role in the …

Breast milk, a source of beneficial microbes and associated benefits for infant health

KE Lyons, CA Ryan, EM Dempsey, RP Ross, C Stanton - Nutrients, 2020 - mdpi.com
Human breast milk is considered the optimum feeding regime for newborn infants due to its
ability to provide complete nutrition and many bioactive health factors. Breast feeding is …

The mean of milk: a review of human milk oligosaccharide concentrations throughout lactation

B Soyyılmaz, MH Mikš, CH Röhrig, M Matwiejuk… - Nutrients, 2021 - mdpi.com
Human milk oligosaccharides (HMOs) are non-digestible and structurally diverse complex
carbohydrates that are highly abundant in human milk. To date, more than 200 different …

[HTML][HTML] Microbiome-based interventions to modulate gut ecology and the immune system

TCA Hitch, LJ Hall, SK Walsh, GE Leventhal, E Slack… - Mucosal …, 2022 - Elsevier
The gut microbiome lies at the intersection between the environment and the host, with the
ability to modify host responses to disease-relevant exposures and stimuli. This is evident in …

The first microbial colonizers of the human gut: composition, activities, and health implications of the infant gut microbiota

C Milani, S Duranti, F Bottacini, E Casey… - Microbiology and …, 2017 - Am Soc Microbiol
The human gut microbiota is engaged in multiple interactions affecting host health during
the host's entire life span. Microbes colonize the neonatal gut immediately following birth …

[HTML][HTML] Human milk oligosaccharides: Shaping the infant gut microbiota and supporting health

C Walsh, JA Lane, D van Sinderen… - Journal of Functional …, 2020 - Elsevier
Human milk oligosaccharides (HMO) are complex sugars which are found in breast milk at
significant concentrations and with unique structural diversity. These sugars are the fourth …

Indole-3-lactic acid associated with Bifidobacterium-dominated microbiota significantly decreases inflammation in intestinal epithelial cells

AM Ehrlich, AR Pacheco, BM Henrick, D Taft, G Xu… - BMC microbiology, 2020 - Springer
Background Bifidobacterium longum subsp. infantis (B. infantis) is a commensal bacterium
that colonizes the gastrointestinal tract of breast-fed infants. B. infantis can efficiently utilize …

Development of the gut microbiota in infancy and its impact on health in later life

M Tanaka, J Nakayama - Allergology International, 2017 - jstage.jst.go.jp
abstract Gut microbial ecology and function are dynamic in infancy, but are stabilized in
childhood. The 'new friends' have a great impact on the development of the digestive tract …

Gut bifidobacteria populations in human health and aging

S Arboleya, C Watkins, C Stanton… - Frontiers in microbiology, 2016 - frontiersin.org
The intestinal microbiota has increasingly been shown to have a vital role in various aspects
of human health. Indeed, several studies have linked alterations in the gut microbiota with …

Human milk oligosaccharides and immune system development

J Plaza-Díaz, L Fontana, A Gil - Nutrients, 2018 - mdpi.com
Maternal milk contains compounds that may affect newborn immunity. Among these are a
group of oligosaccharides that are synthesized in the mammary gland from lactose; these …