[HTML][HTML] Epicardial adipose tissue in contemporary cardiology

G Iacobellis - Nature reviews cardiology, 2022 - nature.com
Interest in epicardial adipose tissue (EAT) is growing rapidly, and research in this area
appeals to a broad, multidisciplinary audience. EAT is unique in its anatomy and …

Obesity and heart failure with preserved ejection fraction: new insights and pathophysiological targets

BA Borlaug, MD Jensen, DW Kitzman… - Cardiovascular …, 2022 - academic.oup.com
Obesity and heart failure with preserved ejection fraction (HFpEF) represent two
intermingling epidemics driving perhaps the greatest unmet health problem in …

Heart failure in the last year: progress and perspective

D Tomasoni, M Adamo, MS Anker… - ESC heart …, 2020 - Wiley Online Library
Research about heart failure (HF) has made major progress in the last years. We give here
an update on the most recent findings. Landmark trials have established new treatments for …

Connecting epicardial adipose tissue and heart failure with preserved ejection fraction: mechanisms, management and modern perspectives

G van Woerden, DJ van Veldhuisen… - European Journal of …, 2022 - Wiley Online Library
Obesity is very common in patients with heart failure with preserved ejection fraction
(HFpEF) and it has been suggested that obesity plays an important role in the …

Characterization of the inflammatory‐metabolic phenotype of heart failure with a preserved ejection fraction: a hypothesis to explain influence of sex on the evolution …

M Packer, CSP Lam, LH Lund… - European Journal of …, 2020 - Wiley Online Library
Accumulating evidence points to the existence of an inflammatory‐metabolic phenotype of
heart failure with a preserved ejection fraction (HFpEF), which is characterized by …

Differential pathophysiological mechanisms in heart failure with a reduced or preserved ejection fraction in diabetes

M Packer - Heart Failure, 2021 - jacc.org
Diabetes promotes the development of both heart failure with a reduced ejection fraction
and heart failure with a preserved ejection fraction through diverse mechanisms, which are …

Heart failure: an update from the last years and a look at the near future

M Riccardi, AM Sammartino, M Piepoli… - ESC heart …, 2022 - Wiley Online Library
In the last years, major progress occurred in heart failure (HF) management. Quadruple
therapy is now mandatory for all the patients with HF with reduced ejection fraction. Whilst …

Cardiac metabolism in HFpEF: from fuel to signalling

F Capone, C Sotomayor-Flores, D Bode… - Cardiovascular …, 2022 - academic.oup.com
Heart failure (HF) is marked by distinctive changes in myocardial uptake and utilization of
energy substrates. Among the different types of HF, HF with preserved ejection fraction …

Assessment of cardiac energy metabolism, function, and physiology in patients with heart failure taking empagliflozin: the randomized, controlled EMPA-VISION trial

MJ Hundertmark, A Adler, C Antoniades, R Coleman… - Circulation, 2023 - Am Heart Assoc
Background: Sodium–glucose co-transporter 2 inhibitors (SGLT2i) have emerged as a
paramount treatment for patients with heart failure (HF), irrespective of underlying reduced …

Epicardial adipose tissue related to left atrial and ventricular function in heart failure with preserved versus reduced and mildly reduced ejection fraction

X Jin, CL Hung, WT Tay, D Soon, D Sim… - European Journal of …, 2022 - Wiley Online Library
Aim Different associations between epicardial adipose tissue (EAT) and cardiac function
have been suggested in patients with heart failure with preserved (HFpEF) versus reduced …