Tumor microenvironment (TME) can serve as the 'soil'for the growth and survival of tumor
cells and function synergically with tumor cells to mediate tumor progression and therapeutic …

Group 3 innate lymphoid cells (ILC3s) are key players in intestinal homeostasis. ER stress is
linked to inflammatory bowel disease (IBD). Here, we used cell culture, mouse models, and …

Notwithstanding the well-recognized involvement of chronic neutrophilic inflammation in the
initiation phase of many types of epithelial cancers, a growing body of evidence has also …

The clearance of dead and dying cells, termed efferocytosis, is a rapid and efficient process
and one that is critical for organismal health. The extraordinary speed and efficiency with …

Neutrophils must navigate accurately towards pathogens in order to destroy invaders and
thus defend our bodies against infection. Here we show that hydrogen peroxide, a potent …

Background: Echinochrome A (EchA) is a pigment from sea urchins. EchA is a
polyhydroxylated 1, 4-naphthoquinone that contains several hydroxyl groups appropriate for …

The effect of low doses of echinochrome A (EchA), a natural polyhydroxy-1, 4-
naphthoquinone pigment from the sea urchin Scaphechinus mirabilis, has been studied in …

Intimal hyperplasia is one of the major complications after stenting, but the underlying
mechanisms remain unclear. Our previous study found that the dipeptidyl peptidase IV (DPP …

Fenitrothion (FNT), an organophosphate pesticide, exerts an immunotoxic effect on
splenocytes. Dietary polyphenol compounds exert antioxidant, anticancer and …

Herpetic simplex keratitis (HSK) mainly represents an immune cell-mediated, and more
specifically, CD4+ T cell-orchestrated inflammatory response to virus invasion. The virus in …