Background Lysosome-associated agents have been implicated as possible chemo-
sensitizers and immune regulators for cancer chemotherapy. We investigated the potential …

Introduction: Despite the current advances in the discovery of the lung cancer biomarkers
and, consequently, in the diagnosis, this pathology continues to be the primary cause of …

Drug resistance has become the main reason for the failure of tumor chemotherapy. Radix
Ophiopogon Japonicus has long been used as traditional Chinese medicine to treat …

Introduction This study was designed to identify a group of bacteria in the human gut
microbiota with specific effects on PD-1-based immunotherapy for patients with non-small …

Lung cancer is one of the most malignant tumors that can form in the human. MicroRNAs
(MiRNAs) play significant role in tumor progression. Human lung cancer tissues and cell …

The high incidence, late diagnosis, and aggressive profile of lung cancer limit the treatment
options, causing a reduced survival rate. Consequently, RNAi-based therapy appears as a …

Purpose: This study aims to compare the mutation profiling of key cancer-related genes in
primary lung cancers and their matched lymph nodes (LN) metastasis. Methods: The gene …

Lung cancer has become one of the types of malignant tumors that seriously threaten
human life worldwide. It is of great significance to detect lung cancer cells from peripheral …

The present study was undertaken to study the function of miRNA-199-3p in the regulation of
human lung cancer growth and metastasis. The results showed significant (P< 0.05) …

In recent years real-time monitoring using liquid biopsies has become a reality in cancer
treatment. A liquid biopsy is defined as the sampling and analysis of circulating components …