Improved scale, multiplexing and resolution are establishing spatial nucleic acid and protein
profiling methods as a major pillar for cellular atlas building of complex samples, from …

The tumor microenvironment (TME) is composed of many different cellular and acellular
components that together drive tumor growth, invasion, metastasis, and response to …

Abstract The Human BioMolecular Atlas Program (HuBMAP) aims to create a multi-scale
spatial atlas of the healthy human body at single-cell resolution by applying advanced …

The rapid pace of innovation in biological imaging and the diversity of its applications have
prevented the establishment of a community-agreed standardized data format. We propose …

Abstract The Human Reference Atlas (HRA) aims to map all of the cells of the human body
to advance biomedical research and clinical practice. This Perspective presents …

A growing community is constructing a next-generation file format (NGFF) for bioimaging to
overcome problems of scalability and heterogeneity. Organized by the Open Microscopy …

Single cell spatial interrogation of the immune-structural interactions in COVID− 19 lungs is
challenging, mainly because of the marked cellular infiltrate and architecturally distorted …

The imminent release of tissue atlases combining multichannel microscopy with single-cell
sequencing and other omics data from normal and diseased specimens creates an urgent …

Deep learning-based approaches are revolutionizing imaging-driven scientific research.
However, the accessibility and reproducibility of deep learning-based workflows for imaging …

The importance of effective research data management (RDM) strategies to support the
generation of Findable, Accessible, Interoperable, and Reusable (FAIR) neuroscience data …