Imidazole ring is an important five‐membered aromatic heterocycle widely present in natural
products and synthetic molecules. The unique structural feature of imidazole ring with …

Breast cancer, a most common malignancy in women, was known to be associated with
steroid hormone estrogen. The discovery of estrogen receptor (ER) gave us not only a …

Indanone is one of the privileged structures in medicinal chemistry and it's commonly
associated with various pharmacologically active compounds. The indanone moiety is found …

Well‐developed asymmetric organocatalysis has been widely incorporated in various
cascade/tandem sequences, providing a simple access to structurally complex target …

A novel series of benzylideneindanone derivatives were designed, synthesized, and
evaluated as multitarget-directed ligands against Alzheimer's disease. The in vitro studies …

Abstract A series of new 4-(3-(4-substitutedphenyl)-3a, 4-dihydro-3 H-indeno [1, 2-c] pyrazol-
2-yl) benzenesulfonamides (7–12) was synthesized starting from 2-(4 …

New radical-triggered multi-component cyclizations of β-alkynyl propenones have been
developed, leading to 50 examples of sulfonated 1-indenones with generally good yields …

A concise copper catalysis strategy for the addition–cyclization of cyclic oxime esters across
1, 6-enynes with high stereoselectivity to generate 1-indanones bearing an all-carbon …

Arylidene indanone (AI) scaffolds are considered as the rigid cousins of chalcones,
incorporating the α, β-unsaturated ketone system of chalcones forming a cyclic 5 membered …

A series of indanone derivatives were designed, synthesized, and tested using a variety of
assays to assess their potential as anti-Alzheimer's disease (AD) agents. The investigations …