Nanoparticle protein corona evolution: from biological impact to biomarker discovery
Nanoparticles exposed to biological fluids such as blood, quickly interact with their
surrounding milieu resulting in a biological coating that results in large part as a function of …
surrounding milieu resulting in a biological coating that results in large part as a function of …
Quantitative mass spectrometry-based proteomics for biomarker development in ovarian cancer
Ovarian cancer is the most lethal gynecologic malignancy among women. Approximately 70–
80% of patients with advanced ovarian cancer experience relapse within five years and …
80% of patients with advanced ovarian cancer experience relapse within five years and …
Serum exosomal miR-377-3p and miR-381-3p as diagnostic biomarkers in colorectal cancer
L Wang, X Song, M Yu, L Niu, Y Zhao, Y Tang… - Future …, 2022 - Taylor & Francis
Aim: This study aimed to identify specific and sensitive exosomal miRNAs in diagnosing
patients with colorectal cancer (CRC). Methods: Serum exosomes were isolated from 175 …
patients with colorectal cancer (CRC). Methods: Serum exosomes were isolated from 175 …
Multiomics of colorectal cancer organoids reveals putative mediators of cancer progression resulting from SMAD4 inactivation
JJ Dijkstra, HK Neikes, S Rezaeifard, X Ma… - Journal of Proteome …, 2022 - ACS Publications
The development of metastasis severely reduces the life expectancy of patients with
colorectal cancer (CRC). Although loss of SMAD4 is a key event in CRC progression, the …
colorectal cancer (CRC). Although loss of SMAD4 is a key event in CRC progression, the …
Circulating serum exosomal long non-coding RNAs FOXD2-AS1, NRIR, and XLOC_009459 as diagnostic biomarkers for colorectal cancer
M Yu, X Song, Y Zhao, X Dong, L Niu, Z Zhang… - Frontiers in …, 2021 - frontiersin.org
Background Exosomes derived from cancer cells encapsulate various kinds of tumor-
specific molecules and thus can interact with adjacent or distant cells to mediate information …
specific molecules and thus can interact with adjacent or distant cells to mediate information …
Proteomic analysis of mucopolysaccharidosis IIIB mouse brain
Mucopolysaccharidosis IIIB (MPS IIIB) is an inherited metabolic disease due to deficiency of
α-N-Acetylglucosaminidase (NAGLU) enzyme with subsequent storage of undegraded …
α-N-Acetylglucosaminidase (NAGLU) enzyme with subsequent storage of undegraded …
Glycoproteomic analysis reveals aberrant expression of complement C9 and fibronectin in the plasma of patients with colorectal cancer
J Chantaraamporn, V Champattanachai… - Proteomes, 2020 - mdpi.com
Colorectal cancer (CRC) is a major cause of cancer mortality. Currently used CRC
biomarkers provide insufficient sensitivity and specificity; therefore, novel biomarkers are …
biomarkers provide insufficient sensitivity and specificity; therefore, novel biomarkers are …
Clinical proteomics in colorectal cancer, a promising tool for improving personalised medicine
A Chauvin, FM Boisvert - Proteomes, 2018 - mdpi.com
Colorectal cancer is the third most common and the fourth most lethal cancer worldwide. In
most of cases, patients are diagnosed at an advanced or even metastatic stage, thus …
most of cases, patients are diagnosed at an advanced or even metastatic stage, thus …
Liposome-embedding silicon microparticle for oxaliplatin delivery in tumor chemotherapy
Mesoporous silicon microparticles (MSMPs) can incorporate drug-carrying nanoparticles
(NPs) into their pores. An NP-loaded MSMP is a multistage vector (MSV) that forms a …
(NPs) into their pores. An NP-loaded MSMP is a multistage vector (MSV) that forms a …
Nano-bio interface between human plasma and niosomes with different formulations indicates protein corona patterns for nanoparticle cell targeting and uptake
E Imperlini, C Celia, A Cevenini, A Mandola, M Raia… - Nanoscale, 2021 - pubs.rsc.org
Unraveling the proteins interacting with nanoparticles (NPs) in biological fluids, such as
blood, is pivotal to rationally design NPs for drug delivery. The protein corona (PrC), formed …
blood, is pivotal to rationally design NPs for drug delivery. The protein corona (PrC), formed …