Nanoparticles exposed to biological fluids such as blood, quickly interact with their
surrounding milieu resulting in a biological coating that results in large part as a function of …

Ovarian cancer is the most lethal gynecologic malignancy among women. Approximately 70–
80% of patients with advanced ovarian cancer experience relapse within five years and …

Aim: This study aimed to identify specific and sensitive exosomal miRNAs in diagnosing
patients with colorectal cancer (CRC). Methods: Serum exosomes were isolated from 175 …

The development of metastasis severely reduces the life expectancy of patients with
colorectal cancer (CRC). Although loss of SMAD4 is a key event in CRC progression, the …

Background Exosomes derived from cancer cells encapsulate various kinds of tumor-
specific molecules and thus can interact with adjacent or distant cells to mediate information …

Mucopolysaccharidosis IIIB (MPS IIIB) is an inherited metabolic disease due to deficiency of
α-N-Acetylglucosaminidase (NAGLU) enzyme with subsequent storage of undegraded …

Colorectal cancer (CRC) is a major cause of cancer mortality. Currently used CRC
biomarkers provide insufficient sensitivity and specificity; therefore, novel biomarkers are …

Colorectal cancer is the third most common and the fourth most lethal cancer worldwide. In
most of cases, patients are diagnosed at an advanced or even metastatic stage, thus …

Mesoporous silicon microparticles (MSMPs) can incorporate drug-carrying nanoparticles
(NPs) into their pores. An NP-loaded MSMP is a multistage vector (MSV) that forms a …

Unraveling the proteins interacting with nanoparticles (NPs) in biological fluids, such as
blood, is pivotal to rationally design NPs for drug delivery. The protein corona (PrC), formed …