The acute loss of kidney function has been diagnosed for many decades using the serum
concentration of creatinine—a muscle metabolite that is an insensitive and non-specific …

KIM-1 (kidney injury molecule 1) is a transmembrane glycoprotein also known as HAVcr-1
and TIM-1 belongs to the T-cell immunoglobulin and mucin domain family (TIM) of proteins …

Partial or complete obstruction of the urinary tract is a common and challenging urological
condition caused by a variety of conditions, including ureteral calculi, ureteral pelvic junction …

In the last decade, management of congenital UPJ obstruction has become progressively
observational despite the lack of precise predictors of outcome. While it is clear that many …

Chronic kidney disease (CKD) development after acute kidney injury (AKI) involves multiple
mechanisms, including inflammation, epithelial-mesenchymal transition (EMT), and …

Multiple urinary biomarkers have been reported in differentiation of nonobstructive dilatation
(NOD) from ureteropelvic junction obstruction (UPJO). In this meta-analysis, we compared …

Pelvi‐ureteric junction obstruction (PUJO) is defined as a functionally significant impairment
of the flow of urine from the kidney's renal pelvis into the proximal ureter. Symptomatically …

Introduction Diagnosing obstruction and thus, assessment of need for surgery in the
management of antenatal hydronephrosis may be challenging. Current diagnostic tests are …

Background: The survival of premature newborns increased in the last decades due to
advances in neonatal care. The physiology of this group is still under investigation, once the …

Congenital anomalies of the urinary tract, and particularly of obstructive nephropathy such
as ureteropelvic junction obstruction (UPJO) in infants, can later lead to chronic kidney …