Polymeric nanomaterials have become a prominent area of research in the field of drug
delivery. Their application in nanomedicine can improve bioavailability, pharmacokinetics …

Polymeric nanocapsules (NC) are versatile mixed vesicular nanocarriers, generally
containing a lipid core with a polymeric wall. They have been first developed over four …

Chagas disease is one of the most important public health problems in Latin America due to
its high mortality and morbidity levels. There is no effective treatment for this disease since …

Chagas disease, caused by the Trypanosoma cruzi parasitic protozoan, is a neglected
tropical disease (NTD) of significant incidence in Latin America. Transmission to humans …

Near-infrared fluorescent dyes, such as IR780, are promising theranostics, acting as
photosensitizers for photodynamic therapy and in vivo tracers in image-guided diagnosis …

Background and Purpose The artemisinin derivative, artemether, has antimalarial activity
with potential neurotoxic and cardiotoxic effects. Artemether in nanocapsules (NC‐ATM) is …

Artemether (ATM) is an effective antimalarial drug that also has a short half-life in the blood.
Furthermore, ATM is also cardiotoxic and is associated with pro-arrhythmogenic risks. We …

Chagas disease (CD) remains neglected and causes high morbidity and mortality. The great
difficulty is the lack of effective treatment. The current drugs cause side effects and have …

Chagas disease remains neglected, and current chemotherapeutics present severe
limitations. Lychnopholide (LYC) at low doses loaded in polymeric poly (d, l-lactide)-block …

Artemether (ATM) cardiotoxicity, its short half-life and low oral bioavailability are the major
limiting factors for its use to treat malaria. The purposes of this work were to study free-ATM …