Organization, function, and therapeutic targeting of the morbillivirus RNA-dependent RNA polymerase complex

J Sourimant, RK Plemper - Viruses, 2016 - mdpi.com
The morbillivirus genus comprises major human and animal pathogens, including the highly
contagious measles virus. Morbilliviruses feature single stranded negative sense RNA …

Bipartite interface of the measles virus phosphoprotein X domain with the large polymerase protein regulates viral polymerase dynamics

V Du Pont, Y Jiang, RK Plemper - PLoS pathogens, 2019 - journals.plos.org
Measles virus (MeV) is a highly contagious, re-emerging, major human pathogen.
Replication requires a viral RNA-dependent RNA polymerase (RdRP) consisting of the large …

Dysregulation of the RIG-I–like receptor pathway signaling by Peste des petits ruminants virus phosphoprotein

P Li, Z Zhu, W Cao, F Yang, X Ma, H Tian… - The Journal of …, 2021 - journals.aai.org
Peste des petits ruminants virus (PPRV) is a Morbillivirus that causes highly contagious and
severe disease in various ruminants. PPRV infection leads to a severe inhibition of host …

Discrimination of mumps virus small hydrophobic gene deletion effects from gene translation effects on virus virulence

T Malik, CW Shegogue, K Werner, L Ngo… - Journal of …, 2011 - Am Soc Microbiol
Deletion of the small hydrophobic (SH) protein of certain paramyxoviruses has been found
to result in attenuation, suggesting that the SH protein is a virulence factor. To investigate the …

Establishment of an in vitro transcription system for Peste des petits ruminant virus

M Yunus, MS Shaila - Virology journal, 2012 - Springer
Background Peste-des-petits ruminants virus (PPRV) is a non segmented negative strand
RNA virus of the genus Morbillivirus within Paramyxoviridae family. Negative strand RNA …

小反刍兽疫病毒P 基因的克隆及其结构与功能分析

翟军军, 窦永喜, 张海瑞, 毛立, 蒙学莲, 骆学农… - 中国农业科学, 2010 - cqvip.com
[目的] 对小反刍兽疫病毒P 基因进行克隆, 并对其结构和功能的关系进行分析,
为研究小反刍兽疫病毒P 蛋白的功能及其在病毒增殖过程中的作用奠定基础.[方法] 利用RT …

The large protein 'L' of Peste-des-petits-ruminants virus exhibits RNA triphosphatase activity, the first enzyme in mRNA capping pathway

MY Ansari, PK Singh, D Rajagopalan, P Shanmugam… - Virus genes, 2019 - Springer
Peste-des-petits-ruminants is a highly contagious and fatal disease of goats and sheep
caused by non-segmented, negative strand RNA virus belonging to the Morbillivirus genus …

[PDF][PDF] 小反刍兽疫病毒结构与功能的研究进展

郗珊珊, 张玲艳, 贾伟娟, 何云江, 王学理 - 微生物学杂志, 2021 - wswx.cnjournals.com
摘要小反刍兽疫病毒属于副黏病毒科麻疹病毒属, 主要感染山羊, 绵羊和野生小反刍兽,
临床症状以发热, 肺炎, 腹泻及呼吸道和消化道黏膜炎症为主要特征. 迄今为止对于小反刍兽疫无 …

Epitope mapping of canine distemper virus phosphoprotein by monoclonal antibodies

A Sugai, T Kooriyama, H Sato… - Microbiology and …, 2009 - Wiley Online Library
The gene for phosphoprotein (P) of CDV encodes three different proteins, P, V, and C. The P
protein is involved in viral gene transcription and replication. In the present study, we …

小反刍兽疫病毒研究进展

王凡, 刘建斌, 祝秀梅 - 现代生物医学进展, 2009 - cqvip.com
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