While ventricular electromechanics is extensively studied in both physiological and
pathological conditions, four-chamber heart models have only been addressed recently; …

The past several decades have seen rapid advances in diagnosis and treatment of
cardiovascular diseases and stroke, enabled by technological breakthroughs in imaging …

We propose a mathematical and numerical model for the simulation of the heart function that
couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and …

Numerical simulations are ubiquitous in mathematics and computational science. Several
industrial and clinical applications entail modeling complex multiphysics systems that evolve …

We propose a machine learning-based method to build a system of differential equations
that approximates the dynamics of 3D electromechanical models for the human heart …

The recruitment of patients for rare or complex cardiovascular diseases is a bottleneck for
clinical trials and digital twins of the human heart have recently been proposed as a viable …

Computational fluid dynamics (CFD) is an important tool for the simulation of the
cardiovascular function and dysfunction. Due to the complexity of the anatomy, the …

Modeling the behavior of biological tissues and organs often necessitates the knowledge of
their shape in the absence of external loads. However, when their geometry is acquired in …

We analyse the haemodynamics of the left atrium, highlighting differences between healthy
individuals and patients affected by atrial fibrillation. The computational study is based on …

We introduce a multiphysics and geometric multiscale computational model, suitable to
describe the hemodynamics of the whole human heart, driven by a four-chamber …