Dental enamel formation and implications for oral health and disease
Dental enamel is the hardest and most mineralized tissue in extinct and extant vertebrate
species and provides maximum durability that allows teeth to function as weapons and/or …
species and provides maximum durability that allows teeth to function as weapons and/or …
[HTML][HTML] Amelogenesis imperfecta; genes, proteins, and pathways
Amelogenesis imperfecta (AI) is the name given to a heterogeneous group of conditions
characterized by inherited developmental enamel defects. AI enamel is abnormally thin, soft …
characterized by inherited developmental enamel defects. AI enamel is abnormally thin, soft …
[HTML][HTML] Protein-mediated enamel mineralization
J Moradian-Oldak - Frontiers in bioscience: a journal and virtual …, 2012 - ncbi.nlm.nih.gov
Enamel is a hard nanocomposite bioceramic with significant resilience that protects the
mammalian tooth from external physical and chemical damages. The remarkable …
mammalian tooth from external physical and chemical damages. The remarkable …
Stem cells for tooth engineering.
G Bluteau, HU Luder, C De Bari… - European cells and …, 2008 - zora.uzh.ch
Tooth development results from sequential and reciprocal interactions between the oral
epithelium and the underlying neural crest-derived mesenchyme. The generation of dental …
epithelium and the underlying neural crest-derived mesenchyme. The generation of dental …
Cenozoic megatooth sharks occupied extremely high trophic positions
Trophic position is a fundamental characteristic of animals, yet it is unknown in many extinct
species. In this study, we ground-truth the 15N/14N ratio of enameloid-bound organic matter …
species. In this study, we ground-truth the 15N/14N ratio of enameloid-bound organic matter …
Osteopontin splice variants and polymorphisms in cancer progression and prognosis
MA Briones-Orta, SE Avendaño-Vázquez… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Osteopontin (OPN) is an extracellular matrix protein that is overexpressed in various cancers
and promotes oncogenic features including cell proliferation, survival, migration, and …
and promotes oncogenic features including cell proliferation, survival, migration, and …
Biomineralization in humans: making the hard choices in life
K Kawasaki, AV Buchanan… - Annual review of genetics, 2009 - annualreviews.org
The skeleton, teeth, and otoconia are normally the only mineralized tissues or organs in the
human body. We describe physiological biomineralization in collagenous matrices as well …
human body. We describe physiological biomineralization in collagenous matrices as well …
Cell fate determination during tooth development and regeneration
TA Mitsiadis, D Graf - Birth Defects Research Part C: Embryo …, 2009 - Wiley Online Library
Teeth arise from sequential and reciprocal interactions between the oral epithelium and the
underlying cranial neural crest‐derived mesenchyme. Their formation involves a precisely …
underlying cranial neural crest‐derived mesenchyme. Their formation involves a precisely …
The enamel protein amelotin is a promoter of hydroxyapatite mineralization
N Abbarin, S San Miguel, J Holcroft… - Journal of Bone and …, 2015 - academic.oup.com
Amelotin (AMTN) is a recently discovered protein that is specifically expressed during the
maturation stage of dental enamel formation. It is localized at the interface between the …
maturation stage of dental enamel formation. It is localized at the interface between the …
[HTML][HTML] Molecular Decay of the Tooth Gene Enamelin (ENAM) Mirrors the Loss of Enamel in the Fossil Record of Placental Mammals
Vestigial structures occur at both the anatomical and molecular levels, but studies
documenting the co-occurrence of morphological degeneration in the fossil record and …
documenting the co-occurrence of morphological degeneration in the fossil record and …