Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

Chronic lower airway infection with Pseudomonas aeruginosa is a major contributor to
morbidity and mortality in individuals suffering from the genetic disease cystic fibrosis (CF) …

Bacterial lineages that chronically infect cystic fibrosis (CF) patients genetically diversify
during infection. However, the mechanisms driving diversification are unknown. By …

Pseudomonas aeruginosa is an opportunistic pathogen, mainly affecting severe patients,
such as those in intensive care units (ICUs). High levels of antibiotic resistance and a long …

This study describes a simple and sensitive approach for visual and point-of-care detection
of P. aeruginosa and its toxin genes based on multiple loop-mediated isothermal …

Pseudomonas aeruginosa uses a complex type III secretion system to inject the toxins ExoS,
ExoT, ExoU, and ExoY into the cytosol of target eukaryotic cells. This system is regulated by …

Pseudomonas aeruginosa is a versatile Gram-negative pathogen known for its ability to
invade the respiratory tract, particularly in cystic fibrosis patients. This review provides a …

Clinical infections by Pseudomonas aeruginosa, a deadly Gram-negative, opportunistic
pathogen of immunocompromised hosts, often involve the formation of antibiotic-resistant …

Immune recognition of pathogen-associated ligands leads to assembly and activation of
inflammasomes, resulting in the secretion of inflammatory cytokines IL-1β and IL-18 and an …

The opportunistic pathogen Pseudomonas aeruginosa expresses a type 3 secretion system
(T3SS) strongly associated with bacterial virulence in murine models and human patients …