The fabrication of scaffolds that accurately recreate the architecture of living tissues is a
major challenge in the field of tissue engineering and regenerative medicine. Core–shell …

Ischemic stroke (IS) causes severe disability and high mortality worldwide. Stem cell (SC)
therapy exhibits unique therapeutic potential for IS that differs from current treatments. SC's …

Stem cell treatment is vital for recovery from traumatic brain injury (TBI). However, severe TBI
usually leads to excessive inflammation and neuroinhibitory factors in the injured brain …

Biomimetic cell culture, which involves creating a biomimetic microenvironment for cells in
vitro by engineering approaches, has aroused increasing interest given that it maintains the …

Despite their clinical success, stem cells (SCs) in the treatment of osteoarthritis (OA) are
limited by lower retention efficiency and restricted paracrine function. The development of …

Microcarriers (MCs) are adaptable therapeutic instruments that may be adjusted to specific
therapeutic uses, making them an appealing alternative for regenerative medicine and drug …

Stem cell–based cell therapeutics and especially those based on human mesenchymal
stem cells (hMSCs) and induced pluripotent stem cells (hiPSCs) are said to have enormous …

Developmental engineering (DE) aims to culture mammalian cells on corresponding
modular scaffolds (scale: micron to millimeter), then assemble these into functional tissues …

Abstract Microcarriers (MCs, typically 50–200 µm) are promising growth supports for high-
throughput cell expansion, with capability to overcome the limitations of surface area …

Conventional microcarriers used for expansion of human mesenchymal stem cells (hMSCs)
require detachment and separation of the cells from the carrier prior to use in clinical …