Molecular basis of physiological heart growth: fundamental concepts and new players

M Maillet, JH Van Berlo, JD Molkentin - Nature reviews Molecular cell …, 2013 - nature.com
The heart hypertrophies in response to developmental signals as well as increased
workload. Although adult-onset hypertrophy can ultimately lead to disease, cardiac …

Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies

BC Bernardo, KL Weeks, L Pretorius… - Pharmacology & …, 2010 - Elsevier
Cardiac hypertrophy can be defined as an increase in heart mass. Pathological cardiac
hypertrophy (heart growth that occurs in settings of disease, eg hypertension) is a key risk …

Electrical and mechanical stimulation of cardiac cells and tissue constructs

WL Stoppel, DL Kaplan, LD Black III - Advanced drug delivery reviews, 2016 - Elsevier
The field of cardiac tissue engineering has made significant strides over the last few
decades, highlighted by the development of human cell derived constructs that have shown …

Peripartum cardiomyopathy: current management and future perspectives

D Hilfiker-Kleiner, A Haghikia, J Nonhoff… - European heart …, 2015 - academic.oup.com
Pregnancy is associated with marked physiological changes challenging the cardiovascular
system. Among the more severe pregnancy associated cardiovascular complications …

[图书][B] Chestnut's obstetric anesthesia: principles and practice e-book

DH Chestnut, CA Wong, LC Tsen, WDN Kee, Y Beilin… - 2014 - books.google.com
From basic science to various anesthesia techniques to complications, the meticulously
updated, fifth edition of Chestnut's Obstetric Anesthesia: Principles and Practice, covers all …

Pregnancy as a cardiac stress model

E Chung, LA Leinwand - Cardiovascular research, 2014 - academic.oup.com
Cardiac hypertrophy occurs during pregnancy as a consequence of both volume overload
and hormonal changes. Both pregnancy-and exercise-induced cardiac hypertrophy are …

Pathophysiology and risk factors of peripartum cardiomyopathy

MF Hoes, Z Arany, J Bauersachs… - Nature Reviews …, 2022 - nature.com
Peripartum cardiomyopathy (PPCM) is a potentially fatal form of idiopathic heart failure with
variable prevalence across different countries and ethnic groups. The cause of PPCM is …

The CaV3.2 T-Type Ca2+ Channel Is Required for Pressure Overload–Induced Cardiac Hypertrophy in Mice

CS Chiang, CH Huang, H Chieng, YT Chang… - Circulation …, 2009 - Am Heart Assoc
Voltage-gated T-type Ca2+ channels (T-channels) are normally expressed during
embryonic development in ventricular myocytes but are undetectable in adult ventricular …

Akt and MAPK signaling mediate pregnancy-induced cardiac adaptation

E Chung, F Yeung… - Journal of Applied …, 2012 - journals.physiology.org
Although the signaling pathways underlying exercise-induced cardiac adaptation have been
extensively studied, little is known about the molecular mechanisms that result in the …

Peripartum cardiomyopathy: recent insights in its pathophysiology

D Hilfiker-Kleiner, K Sliwa, H Drexler - Trends in cardiovascular medicine, 2008 - Elsevier
Peripartum/Postpartum cardiomyopathy (PPCM) is a serious, potentially life-threatening
heart disease of uncertain etiology in previously healthy women. Previous clinical and …