Synthetic α-glucosidase inhibitors as promising anti-diabetic agents: Recent developments and future challenges
Diabetes mellitus is one of the biggest challenges for the scientific community in the 21st
century. It is a well-recognized multifactorial health problem contributes significantly to high …
century. It is a well-recognized multifactorial health problem contributes significantly to high …
Recent developments in synthetic α-glucosidase inhibitors: A comprehensive review with structural and molecular insight
Diabetes mellitus is the prominent metabolic disorder affecting 422 million people around
the globe and cause severe associated problems like kidney disorders, heart and nervous …
the globe and cause severe associated problems like kidney disorders, heart and nervous …
Recent advances of α-glucosidase inhibitors: A comprehensive review
Background: Diabetes mellitus (DM) is a critical health issue prevailing in nearly half a
billion people worldwide. It is one of the most threatening metabolic diseases. Type 2 DM is …
billion people worldwide. It is one of the most threatening metabolic diseases. Type 2 DM is …
The predicted mechanisms and evidence of probiotics on type 2 diabetes mellitus (T2DM)
O Bajinka, K Sylvain Dovi, L Simbilyabo… - … of Physiology and …, 2024 - Taylor & Francis
Type 2 diabetes mellitus (T2DM) is a serious endocrine and metabolic disease that is highly
prevalent and causes high mortality and morbidity rates worldwide. This review aims to …
prevalent and causes high mortality and morbidity rates worldwide. This review aims to …
Synthesis, in Vitro Cholinesterase Inhibition, Molecular Docking, DFT, and ADME Studies of Novel 1,3,4‐Oxadiazole‐2‐Thiol Derivatives
Abstract A series of 1, 3, 4‐oxadiazole‐2‐thiol derivatives bearing various alkyl or aryl
moieties were designed, synthesized, and characterized using modern spectroscopic …
moieties were designed, synthesized, and characterized using modern spectroscopic …
Aspulvinones Suppress Postprandial Hyperglycemia as Potent α-Glucosidase Inhibitors From Aspergillus terreus ASM-1
C Wu, X Cui, L Sun, J Lu, F Li, M Song, Y Zhang… - Frontiers in …, 2021 - frontiersin.org
Chemical investigation of Aspergillus terreus ASM-1 fermentation resulted in the isolation of
three new prenylated aspulvinones V–X (1–3), together with the previously reported …
three new prenylated aspulvinones V–X (1–3), together with the previously reported …
Identification of phenylcarbamoylazinane-1, 3, 4-oxadiazole amides as lipoxygenase inhibitors with expression analysis and in silico studies
In search for new anti-inflammatory agents that inhibit the enzymes of arachidonic acid
pathway as the drug targets, the present article describes the screening of 1, 3, 4-oxadiazole …
pathway as the drug targets, the present article describes the screening of 1, 3, 4-oxadiazole …
Antidiabetic potential of fenugreek (Trigonella foenum‐graecum): A magic herb for diabetes mellitus
Fenugreek (Trigonella foenum‐graecum) is a widely grown dietary herb in Asia, and its
seeds are traditionally used for several diseases, including diabetes. The seeds and leaves …
seeds are traditionally used for several diseases, including diabetes. The seeds and leaves …
A comprehensive review on the antidiabetic activity of oxadiazole derivatives
Oxadiazoles, a class of five membered heterocyclic azoles, are considered to be a versatile
scaffold and is found to be a core moiety of various pharmaceutically active agents …
scaffold and is found to be a core moiety of various pharmaceutically active agents …
Enzyme Inhibition, Kinetic, and Molecular Docking Studies of α-glucosidase
ES Moghadam, MA Faramarzi… - Current Enzyme …, 2020 - ingentaconnect.com
Background: Diabetes mellitus (DM) is an important global health problem especially in
developed countries and insufficient lifestyle induces this phenomenon. Finding efficient …
developed countries and insufficient lifestyle induces this phenomenon. Finding efficient …