Injectable microfluidic hydrogel microspheres for cell and drug delivery

Z Zhao, Z Wang, G Li, Z Cai, J Wu… - Advanced Functional …, 2021 - Wiley Online Library
Microfluidic hydrogel microspheres have been broadly studied across a wide range of
industries and applications, and their use in the medical field, including control cells and …

Potential applications of advanced nano/hydrogels in biomedicine: static, dynamic, multi‐stage, and bioinspired

MH Ayoubi‐Joshaghani, K Seidi, M Azizi… - Advanced Functional …, 2020 - Wiley Online Library
Novel advanced hydrogels can provide a versatile platform for controlled delivery and
release of various cargos, with a myriad of biomedical applications. These gel‐based …

Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing

DR Griffin, MM Archang, CH Kuan, WM Weaver… - Nature materials, 2021 - nature.com
Microporous annealed particle (MAP) scaffolds are flowable, in situ crosslinked,
microporous scaffolds composed of microgel building blocks and were previously shown to …

Influence of microgel fabrication technique on granular hydrogel properties

VG Muir, TH Qazi, J Shan, J Groll… - … Biomaterials Science & …, 2021 - ACS Publications
Bulk hydrogels traditionally used for tissue engineering and drug delivery have numerous
limitations, such as restricted injectability and a nanoscale porosity that reduces cell …

Anisotropic rod‐shaped particles influence injectable granular hydrogel properties and cell invasion

TH Qazi, J Wu, VG Muir, S Weintraub… - Advanced …, 2022 - Wiley Online Library
Granular hydrogels have emerged as a new class of injectable and porous biomaterials that
improve integration with host tissue when compared to solid hydrogels. Granular hydrogels …

Stem cell‐recruiting injectable microgels for repairing osteoarthritis

Y Lei, Y Wang, J Shen, Z Cai, Y Zeng… - Advanced Functional …, 2021 - Wiley Online Library
The differentiation potentials and viability of stem cells are often impaired during cell
isolation and delivery. Inspired by the phenomenon where islands can recruit seabirds for …

Sticking together: injectable granular hydrogels with increased functionality via dynamic covalent inter‐particle crosslinking

VG Muir, TH Qazi, S Weintraub, BO Torres Maldonado… - Small, 2022 - Wiley Online Library
Granular hydrogels are an exciting class of microporous and injectable biomaterials that are
being explored for many biomedical applications, including regenerative medicine, 3D …

Assembling microgels via dynamic cross-linking reaction improves printability, microporosity, tissue-adhesion, and self-healing of microgel bioink for extrusion …

Q Feng, D Li, Q Li, H Li, Z Wang, S Zhu… - … Applied Materials & …, 2022 - ACS Publications
Extrusion bioprinting has been widely used to fabricate complicated and heterogeneous
constructs for tissue engineering and regenerative medicine. Despite the remarkable …

A low-temperature-printed hierarchical porous sponge-like scaffold that promotes cell-material interaction and modulates paracrine activity of MSCs for vascularized …

M Lian, B Sun, Y Han, B Yu, W Xin, R Xu, B Ni, W Jiang… - Biomaterials, 2021 - Elsevier
Mesenchymal stem cells (MSCs) secrete paracrine trophic factors that are beneficial for
tissue regeneration. In this study, a sponge-like scaffold with hierarchical and interconnected …

Building block properties govern granular hydrogel mechanics through contact deformations

DB Emiroglu, A Bekcic, D Dranseike, X Zhang… - Science …, 2022 - science.org
Granular hydrogels have been increasingly exploited in biomedical applications, including
wound healing and cardiac repair. Despite their utility, design guidelines for engineering …