Spinocerebellar ataxia (SCA) is a part of the cerebellar neurodegenerative disease group
that is diverse in genetics and phenotypes. It usually shows autosomal dominant …

Spinocerebellar ataxia type 1 (SCA1) is characterized by progressive cerebellar ataxia,
dysarthria, and eventual deterioration of bulbar functions. Early in the disease, affected …

The relationship between optical coherence tomography (OCT) measurements of the retinal
structures has been described for various neurological diseases including Multiple Sclerosis …

Spinocerebellar ataxia type 1 (SCA-ATXN1) is an autosomal dominant, neurodegenerative
disease, caused by CAG repeat expansion in the ataxin-1 gene (ATXN1). In isolated reports …

Background Neurodegeneration affects the brain and peripheral nervous system in
spinocerebellar ataxia type 3 (SCA3). As the retina is also involved, studying the retinal …

Background ATXN2 is the causative gene of spinocerebellar ataxia type 2 (SCA2) and has
been implicated in glaucoma pathogenesis. Therefore, studying ocular changes in SCA2 …

Background Neurodegenerative ataxias are devastating disorders of the cerebellum and
spinal cord, accompanied by death of retinal ganglion cells, leading to relentlessly …

Hereditary optic neuropathies (HONs) are a class of genetic disorders that may lead to
vision loss due to either acute or progressive injury to the optic nerve. Although HONs may …

Die autosomal-dominant vererbten Spinozerebellären Ataxien sind eine Gruppe
neurodegenerativer Erkrankungen, die durch eine progrediente Ataxie gekennzeichnet …

Die retinale optische Kohärenztomographie (OCT) ist ein vielversprechender Biomarker bei
neurodegenerativen und neuroinflammatorischen Erkrankungen. Multiple Sklerose (MS) …