Extracellular vesicles in fungi: past, present, and future perspectives

J Rizzo, ML Rodrigues, G Janbon - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
Extracellular vesicles (EVs) have garnered much interest in the cell biology and biomedical
research fields. Many studies have reported the existence of EVs in all types of living cells …

Extracellular vesicles in the fungi kingdom

M Liebana-Jordan, B Brotons, JM Falcon-Perez… - International Journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are membranous, rounded vesicles released by prokaryotic and
eukaryotic cells in their normal and pathophysiological states. These vesicles form a network …

Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING

H Brown Harding, GN Kwaku, CM Reardon… - Nature …, 2024 - nature.com
The host type I interferon (IFN) pathway is a major signature of inflammation induced by the
human fungal pathogen, Candida albicans. However, the molecular mechanism for …

Communication is key: extracellular vesicles as mediators of infection and defence during host–microbe interactions in animals and plants

H U. Stotz, D Brotherton, J Inal - FEMS microbiology reviews, 2022 - academic.oup.com
Extracellular vesicles (EVs) are now understood to be ubiquitous mediators of cellular
communication. In this review, we suggest that EVs have evolved into a highly regulated …

Cryptococcus extracellular vesicles properties and their use as vaccine platforms

J Rizzo, SSW Wong, AD Gazi… - Journal of …, 2021 - Wiley Online Library
Whereas extracellular vesicle (EV) research has become commonplace in different
biomedical fields, this field of research is still in its infancy in mycology. Here we provide a …

Extracellular vesicles regulate biofilm formation and yeast-to-hypha differentiation in Candida albicans

L Honorato, JFD de Araujo, CC Ellis, AC Piffer… - MBio, 2022 - Am Soc Microbiol
In this study, we investigated the influence of fungal extracellular vesicles (EVs) during
biofilm formation and morphogenesis in Candida albicans. Using crystal violet staining and …

Extracellular Vesicles from Fusarium graminearum Contain Protein Effectors Expressed during Infection of Corn

D Garcia-Ceron, RGT Lowe, JA McKenna, LM Brain… - Journal of Fungi, 2021 - mdpi.com
Fusarium graminearum (Fgr) is a devastating filamentous fungal pathogen that causes
diseases in cereals, while producing mycotoxins that are toxic for humans and animals, and …

The emerging role of extracellular vesicles in fungi: A double-edged sword

Y Lai, B Jiang, F Hou, X Huang, B Ling, H Lu… - Frontiers in …, 2023 - frontiersin.org
Fungi are eukaryotic microorganisms found in nature, which can invade the human body
and cause tissue damage, inflammatory reactions, organ dysfunctions, and diseases. These …

Harnessing the immune response to fungal pathogens for vaccine development

A Rivera, J Lodge, C Xue - Annual review of microbiology, 2022 - annualreviews.org
Invasive fungal infections are emerging diseases that kill over 1.5 million people per year
worldwide. With the increase of immunocompromised populations, the incidence of invasive …

Isolation, purification, and application of protoplasts and transient expression systems in plants

K Chen, J Chen, X Pi, LJ Huang, N Li - International Journal of Molecular …, 2023 - mdpi.com
Protoplasts, derived from plant cells, exhibit remarkable totipotency and hold significant
value across a wide spectrum of biological and biotechnological applications. These …