Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies

S Xu, I Ilyas, J Weng - Acta Pharmacologica Sinica, 2023 - nature.com
The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …

An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug Resistance …, 2021 - Elsevier
The COVID-19 pandemic is one of the greatest threats to human health in the 21st century
with more than 257 million cases and over 5.17 million deaths reported worldwide (as of …

Endothelial dysfunction in atherosclerotic cardiovascular diseases and beyond: from mechanism to pharmacotherapies

S Xu, I Ilyas, PJ Little, H Li, D Kamato, X Zheng… - Pharmacological …, 2021 - ASPET
The endothelium, a cellular monolayer lining the blood vessel wall, plays a critical role in
maintaining multiorgan health and homeostasis. Endothelial functions in health include …

COVID-19 and diabetes mellitus: from pathophysiology to clinical management

S Lim, JH Bae, HS Kwon, MA Nauck - Nature Reviews Endocrinology, 2021 - nature.com
Initial studies found increased severity of coronavirus disease 2019 (COVID-19), caused by
infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in patients …

Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics

Y Duan, K Gong, S Xu, F Zhang, X Meng… - Signal Transduction and …, 2022 - nature.com
Disturbed cholesterol homeostasis plays critical roles in the development of multiple
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …

COVID-19 is, in the end, an endothelial disease

P Libby, T Lüscher - European heart journal, 2020 - academic.oup.com
The vascular endothelium provides the crucial interface between the blood compartment
and tissues, and displays a series of remarkable properties that normally maintain …

[HTML][HTML] Large-scale multi-omic analysis of COVID-19 severity

KA Overmyer, E Shishkova, IJ Miller, J Balnis… - Cell systems, 2021 - cell.com
We performed RNA-seq and high-resolution mass spectrometry on 128 blood samples from
COVID-19-positive and COVID-19-negative patients with diverse disease severities and …

Genetic screens identify host factors for SARS-CoV-2 and common cold coronaviruses

R Wang, CR Simoneau, J Kulsuptrakul, M Bouhaddou… - Cell, 2021 - cell.com
The Coronaviridae are a family of viruses that cause disease in humans ranging from mild
respiratory infection to potentially lethal acute respiratory distress syndrome. Finding host …

Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks

WM Schneider, JM Luna, HH Hoffmann… - Cell, 2021 - cell.com
Summary The coronavirus disease 2019 (COVID-19) pandemic has claimed the lives of
over one million people worldwide. The causative agent, severe acute respiratory syndrome …

Current status of plant metabolite-based fabrication of copper/copper oxide nanoparticles and their applications: a review

KS Siddiqi, A Husen - Biomaterials Research, 2020 - spj.science.org
Since green mode of nanoparticles (NPs) synthesis is simple, advantageous and
environment friendly relative to chemical and physical procedures, various plant species …