Chemical dissection of selective myeloid leukemia-1 inhibitors: How they were found and evolved

L Wang, Y Chen, M Zhang, J Liu, H Li, M Liu… - European Journal of …, 2024 - Elsevier
Abstract Myeloid cell leukemia-1 (MCL-1), a key anti-apoptotic protein within the BCL-2
family, is essential in regulating cell survival, particularly in cancer, where its overexpression …

Mechanistic Characterization of CDK9 Inhibition in T-Cell Lymphoma

NAM Ksionsko - 2024 - ediss.uni-goettingen.de
Lymphomas represent a heterogeneous group of cancers that emerge when lymphocytes
undergo malignant transformation. This group encompasses several lymphoid malignancies …