Abstract Background This is Part 2 of the first consensus guidelines for optimal care of
patients undergoing emergency laparotomy (EL) using an Enhanced Recovery After …

Peri‐operative neurocognitive disorders are the most common complication experienced by
older individuals undergoing anaesthesia and surgery. Peri‐operative neurocognitive …

Background The delirium-sparing effect of nighttime dexmedetomidine has not been studied
after surgery. We hypothesised that a nighttime dose of dexmedetomidine would reduce the …

Background Microglial polarization toward pro-inflammatory M1 phenotype are major
contributors to the development of perioperative neurocognitive disorders (PNDs). Metabolic …

Objective: This study aims to identify blood biomarkers of postoperative delirium.
Background: Phosphorylated tau at threonine 217 (Tau-PT217) and 181 (Tau-PT181) are …

Background Delirium in hospitalized patients is a major public health issue, yet delirium is
often unrecognized and missed during inpatient admission. The objective of this study was …

Objective Although animal models suggest a role for blood–brain barrier dysfunction in
postoperative delirium‐like behavior, its role in postoperative delirium and postoperative …

Study objective To assess the incidence of postoperative delirium and its outcomes in older
non-cardiac surgical patients. Design A systematic review and meta-analysis with multiple …

For years, postoperative cognitive outcomes have steadily garnered attention, and in the
past decade, they have remained at the forefront. This prominence is primarily due to …

Advances in spine surgery enable technically safe interventions in older patients with
disabling spine disease, yet postoperative delirium (POD) poses a serious risk for …