[HTML][HTML] Bioactive compounds in oxidative stress-mediated diseases: targeting the NRF2/ARE signaling pathway and epigenetic regulation

M Thiruvengadam, B Venkidasamy, U Subramanian… - Antioxidants, 2021 - mdpi.com
Oxidative stress is a pathological condition occurring due to an imbalance between the
oxidants and antioxidant defense systems in the body. Nuclear factor E2-related factor 2 …

Astaxanthin: A super antioxidant from microalgae and its therapeutic potential

S Kumar, R Kumar, Diksha, A Kumari… - Journal of Basic …, 2022 - Wiley Online Library
Astaxanthin is a ketocarotenoid, super antioxidant molecule. It has higher antioxidant activity
than a range of carotenoids, thus has applications in cosmetics, aquaculture, nutraceuticals …

[HTML][HTML] Pharmaceutical and nutraceutical potential of natural bioactive pigment: astaxanthin

AD Patil, PJ Kasabe, PB Dandge - Natural products and bioprospecting, 2022 - Springer
Abstract Astaxanthin (3, 3′-dihydroxy-β, β-carotene-4, 4′-dione) is an orange-red,
lipophilic keto-carotenoid pigment. It is majorly found in marine ecosystems particularly in …

[HTML][HTML] Anti-inflammatory and anticancer effects of microalgal carotenoids

J Ávila-Román, S García-Gil, A Rodríguez-Luna… - Marine Drugs, 2021 - mdpi.com
Acute inflammation is a key component of the immune system's response to pathogens, toxic
agents, or tissue injury, involving the stimulation of defense mechanisms aimed to removing …

Astaxanthin anticancer effects are mediated through multiple molecular mechanisms: A systematic review

I Faraone, C Sinisgalli, A Ostuni, MF Armentano… - Pharmacological …, 2020 - Elsevier
During the latest decades, the interest on the effectiveness of natural compounds and their
impact on human health constantly increased, especially on those demonstrating to be …

[HTML][HTML] Neuroprotective potentials of marine algae and their bioactive metabolites: Pharmacological insights and therapeutic advances

MA Hannan, R Dash, MN Haque, M Mohibbullah… - Marine drugs, 2020 - mdpi.com
Beyond their significant contribution to the dietary and industrial supplies, marine algae are
considered to be a potential source of some unique metabolites with diverse health benefits …

[HTML][HTML] Epigenetic regulation of NRF2/KEAP1 by phytochemicals

S Bhattacharjee, RH Dashwood - Antioxidants, 2020 - mdpi.com
Epigenetics has provided a new dimension to our understanding of nuclear factor erythroid
2–related factor 2/Kelch-like ECH-associated protein 1 (human NRF2/KEAP1 and murine …

The colorful world of carotenoids: A profound insight on therapeutics and recent trends in nano delivery systems

S Maghsoudi, B Taghavi Shahraki… - Critical reviews in …, 2022 - Taylor & Francis
The therapeutic effects of carotenoids as dietary supplements to control or even treat some
specific diseases including diabetic retinopathy, cardiovascular diseases, bacterial …

[HTML][HTML] A systematic review on marine algae-derived fucoxanthin: An update of pharmacological insights

M Mohibbullah, MN Haque, AAM Sohag, MT Hossain… - Marine Drugs, 2022 - mdpi.com
Fucoxanthin, belonging to the xanthophyll class of carotenoids, is a natural antioxidant
pigment of marine algae, including brown macroalgae and diatoms. It represents 10% of the …

[HTML][HTML] The role of natural products in targeting cardiovascular diseases via Nrf2 pathway: novel molecular mechanisms and therapeutic approaches

BK Ooi, KG Chan, BH Goh, WH Yap - Frontiers in Pharmacology, 2018 - frontiersin.org
Cardiovascular diseases (CVDs) are closely linked to cellular oxidative stress and
inflammation. This may be resulted from the imbalance generation of reactive oxygen …