In search of a pan-coronavirus vaccine: next-generation vaccine design and immune mechanisms
S Cankat, MU Demael, L Swadling - Cellular & molecular immunology, 2024 - nature.com
Members of the coronaviridae family are endemic to human populations and have caused
several epidemics and pandemics in recent history. In this review, we will discuss the …
several epidemics and pandemics in recent history. In this review, we will discuss the …
Silent battles: immune responses in asymptomatic SARS-CoV-2 infection
N Le Bert, T Samandari - Cellular & Molecular Immunology, 2024 - nature.com
SARS-CoV-2 infections manifest with a broad spectrum of presentations, ranging from
asymptomatic infections to severe pneumonia and fatal outcomes. This review centers on …
asymptomatic infections to severe pneumonia and fatal outcomes. This review centers on …
Post-pandemic memory T cell response to SARS-CoV-2 is durable, broadly targeted, and cross-reactive to the hypermutated BA. 2.86 variant
R Nesamari, MA Omondi, R Baguma, MA Höft… - Cell host & …, 2024 - cell.com
Ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolution has
given rise to recombinant Omicron lineages that dominate globally (XBB. 1), as well as the …
given rise to recombinant Omicron lineages that dominate globally (XBB. 1), as well as the …
Memory T cells effectively recognize the SARS-CoV-2 hypermutated BA. 2.86 variant
T cells are critical in mediating the early control of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) breakthrough infection. However, it remains unknown whether …
coronavirus 2 (SARS-CoV-2) breakthrough infection. However, it remains unknown whether …
Correlates of protection against symptomatic SARS-CoV-2 in vaccinated children
The paucity of information on longevity of vaccine-induced immune responses and
uncertainty of the correlates of protection hinder the development of evidence-based COVID …
uncertainty of the correlates of protection hinder the development of evidence-based COVID …
Immunological imprinting shapes the specificity of human antibody responses against SARS-CoV-2 variants
The spike glycoprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
continues to accumulate substitutions, leading to breakthrough infections of vaccinated …
continues to accumulate substitutions, leading to breakthrough infections of vaccinated …
B-cell and antibody responses to SARS-CoV-2: infection, vaccination, and hybrid immunity
D Lapuente, TH Winkler, M Tenbusch - Cellular & Molecular …, 2024 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019
prompted scientific, medical, and biotech communities to investigate infection-and vaccine …
prompted scientific, medical, and biotech communities to investigate infection-and vaccine …
Cross-reactivity assessment of vaccine-derived SARS-CoV-2 T cell responses against BA. 2.86 and JN. 1
The SARS-CoV-2 Omicron sub-variants BA. 2.86 and JN. 1 contain multiple mutations in the
spike protein that were not present in previous variants of concern and Omicron sub …
spike protein that were not present in previous variants of concern and Omicron sub …
Extraordinary Titer and Broad Anti-SARS-CoV-2 Neutralization Induced by Stabilized RBD Nanoparticles from Strain BA. 5
Z Wang, B Zhang, L Ou, Q Qiu, L Wang, T Bylund… - Vaccines, 2023 - mdpi.com
The receptor-binding domain (RBD) of the SARS-CoV-2 spike is a primary target of
neutralizing antibodies and a key component of licensed vaccines. Substantial mutations in …
neutralizing antibodies and a key component of licensed vaccines. Substantial mutations in …
SARS-CoV-2 breakthrough infections enhance T cell response magnitude, breadth, and epitope repertoire
Little is known about the effect of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2 or SARS2) vaccine breakthrough infections (BTIs) on the magnitude and breadth of …
CoV-2 or SARS2) vaccine breakthrough infections (BTIs) on the magnitude and breadth of …