[HTML][HTML] Brain docosahexaenoic acid uptake and metabolism

RJS Lacombe, R Chouinard-Watkins… - Molecular Aspects of …, 2018 - Elsevier
Docosahexaenoic acid (DHA) is the most abundant n-3 polyunsaturated fatty acid in the
brain where it serves to regulate several important processes and, in addition, serves as a …

Omega-3 fatty acid deficiencies in neurodevelopment, aggression and autonomic dysregulation: opportunities for intervention

JR Hibbeln, TA Ferguson… - International Review of …, 2006 - Taylor & Francis
Mechanisms by which aggressive and depressive disorders may be exacerbated by
nutritional deficiencies in omega-3 fatty acids are considered. Early developmental …

DHA improves cognition and prevents dysfunction of entorhinal cortex neurons in 3xTg-AD mice

D Arsenault, C Julien, C Tremblay, F Calon - PloS one, 2011 - journals.plos.org
Defects in neuronal activity of the entorhinal cortex (EC) are suspected to underlie the
symptoms of Alzheimer's disease (AD). Whereas neuroprotective effects of …

Omega-3 polyunsaturated fatty acids increase the neurite outgrowth of rat sensory neurones throughout development and in aged animals

LG Robson, SC Dyall, D Sidloff, AT Michael-Titus - Neurobiology of aging, 2010 - Elsevier
Polyunsaturated fatty acids (PUFA) of the omega-3 series and omega-6 series modulate
neurite outgrowth in immature neurones. However, it has not been determined if their …

[HTML][HTML] The benefit of docosahexaenoic acid for the adult brain in aging and dementia

N Salem Jr, M Vandal, F Calon - Prostaglandins, leukotrienes and …, 2015 - Elsevier
A brief overview of the evidence for omega-3 fatty acids and, in particular, of
docosahexaenoic acid (DHA), involvement in cognition and in dementia is given. Two …

Detailed characterization of the lipid composition of detergent-resistant membranes from photoreceptor rod outer segment membranes

RE Martin, MH Elliott, RS Brush… - … & visual science, 2005 - iovs.arvojournals.org
purpose. In recent years, detergent-resistant membranes (DRMs) have been isolated in in
vitro models of lipid rafts, from photoreceptor outer segments (ROS), and the localization of a …

ELOVL4 protein preferentially elongates 20: 5n3 to very long chain PUFAs over 20: 4n6 and 22: 6n3

M Yu, A Benham, S Logan, RS Brush… - Journal of Lipid …, 2012 - ASBMB
We hypothesized that reduction/loss of very long chain PUFAs (VLC-PUFAs) due to
mutations in the ELOngase of very long chain fatty acid-4 (ELOVL4) protein contributes to …

Expression of E‐FABP in PC12 cells increases neurite extension during differentiation: involvement of n‐3 and n‐6 fatty acids

JW Liu, FG Almaguel, L Bu, DD De Leon… - Journal of …, 2008 - Wiley Online Library
Epidermal fatty acid‐binding protein (E‐FABP), a member of the family of FABPs, exhibits a
robust expression in neurons during axonal growth in development and in nerve …

Altered brain neurotrophins at birth: consequence of imbalance in maternal folic acid and vitamin B12 metabolism

P Sable, K Dangat, A Kale, S Joshi - Neuroscience, 2011 - Elsevier
Folic acid fortification to pregnant women is suggested to mask vitamin B12 deficiency
leading to adverse neurologic consequences. The present study examines the effect of …

Long-chain polyunsaturated fatty acid accretion in brain

K Qi, M Hall, RJ Deckelbaum - Current Opinion in Clinical …, 2002 - journals.lww.com
Brain is highly enriched in long-chain polyunsaturated fatty acids (PUFAs), particularly
arachidonic acid and docosahexaenoic acid, which play important roles in brain structural …