SUMMARY A major part of organismal complexity and versatility of prokaryotes resides in
their ability to fine-tune gene expression to adequately respond to internal and external …

Escherichia coli is the best-known model for the biotechnological production of many
biotechnological products, including housekeeping and heterologous primary and …

Gene regulatory interactions are context dependent, active in some cellular states but not in
others. Stochastic fluctuations, or'noise', in gene expression propagate through active, but …

L-aspartate is an important 4-carbon platform compound that can be used as the precursor
of numerous chemical products. The bioproduction of L-aspartate directly from biomass …

Gene regulation networks contain recurring circuit patterns called network motifs. One of the
most common network motif is the incoherent type 1 feed‐forward loop (I1‐FFL), in which an …

In Escherichia coli, several systems are known to transport glucose into the cytoplasm. The
main glucose uptake system under batch conditions is the glucose phosphoenolpyruvate …

Although metabolic networks have been reconstructed on a genome scale, the
corresponding reconstruction and integration of governing transcriptional regulatory …

Aims: To complement our proteome study, whole‐transcriptome analyses were utilized here
to identify proteins related to degrading cis‐1, 2‐dichloroethylene (cis‐DCE). Methods and …

Central metabolism is a topic that has been studied for decades, and yet, this process is still
not fully understood in Escherichia coli, perhaps the most amenable and well-studied model …

The function of living cells is controlled by complex regulatory networks that are built of a
wide diversity of interacting molecular components. The sheer size and intricacy of …