Considerations for selecting cognitive endpoints and psychological patient-reported outcomes for clinical trials in pediatric patients with sickle cell disease
Pediatric patients with sickle cell disease (SCD) experience a range of medical
complications that result in significant morbidity and mortality. Recent advances in …
complications that result in significant morbidity and mortality. Recent advances in …
Efficacy of dapagliflozin versus sitagliptin on cardiometabolic risk factors in Japanese patients with type 2 diabetes: a prospective, randomized study (DIVERSITY-CVR …
A Fuchigami, F Shigiyama, T Kitazawa, Y Okada… - Cardiovascular …, 2020 - Springer
Background Few prospective studies have compared the cardiovascular benefits of sodium-
glucose cotransporter-2 (SGLT2) inhibitors and dipeptidyl peptidase 4 (DPP-4) inhibitors …
glucose cotransporter-2 (SGLT2) inhibitors and dipeptidyl peptidase 4 (DPP-4) inhibitors …
Body composition in type 2 diabetes: change in quality and not just quantity that matters
JD Solanki, AH Makwana, HB Mehta… - … journal of preventive …, 2015 - journals.lww.com
Background: Deranged body fat and muscle mass are aftermaths of uncontrolled diabetes.
Anthropometric methods like body mass index (BMI) do not give qualitative inferences like …
Anthropometric methods like body mass index (BMI) do not give qualitative inferences like …
Impact of medication nonadherence on stroke recurrence and mortality in patients after first‐ever ischemic stroke: Insights from registry data in Singapore
SH Yeo, MPHS Toh, SH Lee, RCS Seet… - … and drug safety, 2020 - Wiley Online Library
Purpose This retrospective cohort study aims to examine adherence to secondary stroke
preventive medications and their association with risk of stroke recurrence and mortality in …
preventive medications and their association with risk of stroke recurrence and mortality in …
A multiplicity of targets: evaluating composite endpoint studies of the GLP-1 receptor agonists in type 2 diabetes
SA Ross - Current Medical Research and Opinion, 2015 - Taylor & Francis
Objective: Current type 2 diabetes (T2D) treatment guidelines include weight maintenance
or loss, avoidance of hypoglycemia, and targets for blood pressure and circulating lipids, in …
or loss, avoidance of hypoglycemia, and targets for blood pressure and circulating lipids, in …
Yoga-based lifestyle treatment and composite treatment goals in Type 2 Diabetes in a rural South Indian setup-a retrospective study
G Arumugam, R Nagarathna, V Majumdar, M Singh… - Scientific reports, 2020 - nature.com
This multicentre retrospective study examined the effects of adjunct yoga-treatment in
achieving composite cardiovascular goals for type 2 diabetes (T2D), set forth by the …
achieving composite cardiovascular goals for type 2 diabetes (T2D), set forth by the …
Composite endpoint to evaluate complement inhibition therapy in patients with paroxysmal nocturnal hemoglobinuria
A Kulasekararaj, A Glasmacher, P Liu… - European Journal of …, 2022 - Wiley Online Library
This study developed and explored a novel composite endpoint to assess the overall impact
that treatment can have on patients living with paroxysmal nocturnal hemoglobinuria (PNH) …
that treatment can have on patients living with paroxysmal nocturnal hemoglobinuria (PNH) …
Quantiles based personalized treatment selection for multivariate outcomes and multiple treatments
KB Kulasekera, C Siriwardhana - Statistics in medicine, 2022 - Wiley Online Library
In this work, we propose a method for individualized treatment selection when there are
correlated multiple responses for the K treatment (K≥ 2) scenario. Here we use ranks of …
correlated multiple responses for the K treatment (K≥ 2) scenario. Here we use ranks of …
Effect of current glycemic control on qualitative body composition in sedentary ambulatory Type 2 diabetics
JD Solanki, AH Makwana, HB Mehta… - Nigerian Medical …, 2016 - journals.lww.com
Background: Obesity and Type 2 diabetes mellitus are on rise with cause–effect relationship.
Diabetics monitor blood sugar, neglecting qualitative body composition, leaving residual …
Diabetics monitor blood sugar, neglecting qualitative body composition, leaving residual …
Greater Combined Reductions of HbA1c ≥ 1.0% and Body Weight Loss ≥ 5.0% or ≥ 10.0% with Orally Administered Semaglutide Versus Comparators
KM Dungan, L Bardtrum, E Christiansen, J Eliasson… - Diabetes Therapy, 2023 - Springer
Introduction A post hoc analysis of the PIONEER 1–5 and 8 trials assessed the clinically
relevant composite endpoints of HbA1c (glycated haemoglobin) reduction≥ 1% and body …
relevant composite endpoints of HbA1c (glycated haemoglobin) reduction≥ 1% and body …