Blood loss and subsequent transfusions are associated with major morbidity and mortality.
The use of antifibrinolytics can reduce blood loss in cardiac surgery, trauma, orthopedic …

Intravenous tranexamic acid (TXA) has been shown to be effective in reducing blood loss
and the need for transfusion after joint replacement. Recently, there has been interest in …

The management of perioperative bleeding involves multiple assessments and strategies to
ensure appropriate patient care. Initially, it is important to identify those patients with an …

Background A growing body of published research on tranexamic acid (TXA) suggests that it
is effective in reducing blood loss and the risk for transfusion in total knee arthroplasty (TKA) …

Background: Abundant literature regarding the use of intravenous tranexamic acid (TXA) in
primary total knee replacement is available. Randomized controlled trials have confirmed …

Background The optimal dosage and timing of tranexamic acid (TXA) in total knee
arthroplasty (TKA) are undetermined. The purpose of this study was to explore the effect of …

Background: Tourniquet use during primary total knee arthroplasty is thought to reduce
intraoperative blood loss and improve visibility. Our goal was to investigate whether …

Background Tranexamic acid (TXA) is effective in reducing blood loss in total joint
arthroplasty (TJA), but concerns still remain regarding the drug's safety. The purpose of this …

Perioperative bleeding and postsurgical hemorrhage are common in invasive surgical
procedures, including orthopedic surgery. Tranexamic acid (TXA) is a pharmacologic agent …

Background: Approximately one-third of patients undergoing total hip replacement surgery
require one to three units of blood postoperatively. Tranexamic acid is a synthetic …