Impaired adipogenesis and dysfunctional adipose tissue in human hypertrophic obesity
A Hammarstedt, S Gogg, S Hedjazifar… - Physiological …, 2018 - journals.physiology.org
The subcutaneous adipose tissue (SAT) is the largest and best storage site for excess lipids.
However, it has a limited ability to expand by recruiting and/or differentiating available …
However, it has a limited ability to expand by recruiting and/or differentiating available …
Epigenetic signatures underlying inflammation: An interplay of nutrition, physical activity, metabolic diseases, and environmental factors for personalized nutrition
Aim and objective Emerging translational evidence suggests that epigenetic alterations
(DNA methylation, miRNA expression, and histone modifications) occur after external stimuli …
(DNA methylation, miRNA expression, and histone modifications) occur after external stimuli …
MicroRNAs in obesity and related metabolic disorders
JF Landrier, A Derghal, L Mounien - Cells, 2019 - mdpi.com
Metabolic disorders are characterized by the inability to properly use and/or store energy.
The burdens of metabolic disease, such as obesity or diabetes, are believed to arise through …
The burdens of metabolic disease, such as obesity or diabetes, are believed to arise through …
Role of microRNAs in obesity and obesity-related diseases
G Iacomino, A Siani - Genes & nutrition, 2017 - Springer
In recent years, the link between regulatory microRNAs (miRNAs) and diseases has been
the object of intensive research. miRNAs have emerged as key mediators of metabolic …
the object of intensive research. miRNAs have emerged as key mediators of metabolic …
Exosomes from the tumour-adipocyte interplay stimulate beige/brown differentiation and reprogram metabolism in stromal adipocytes to promote tumour progression
Q Wu, J Li, Z Li, S Sun, S Zhu, L Wang, J Wu… - Journal of Experimental …, 2019 - Springer
Background Emerging evidence supports the pivotal roles of adipocytes in breast cancer
progression. Tumour induced beige/brown adipose tissue differentiation contributes to the …
progression. Tumour induced beige/brown adipose tissue differentiation contributes to the …
Anti-obesity effect of carotenoids: direct impact on adipose tissue and adipose tissue-driven indirect effects
This review summarizes current knowledge on the biological relevance of carotenoids and
some of their metabolites in obesity management. The relationship between carotenoids …
some of their metabolites in obesity management. The relationship between carotenoids …
The impact of adipose tissue–derived miRNAs in metabolic syndrome, obesity, and cancer
GS Heyn, LH Corrêa, KG Magalhães - Frontiers in endocrinology, 2020 - frontiersin.org
Obesity is a multifactorial and complex condition that is characterized by abnormal and
excessive white adipose tissue accumulation, which can lead to the development of …
excessive white adipose tissue accumulation, which can lead to the development of …
Human brown adipose tissue and metabolic health: potential for therapeutic avenues
R Singh, A Barrios, G Dirakvand, S Pervin - Cells, 2021 - mdpi.com
Obesity-associated metabolic abnormalities comprise a cluster of conditions including
dyslipidemia, insulin resistance, diabetes and cardiovascular diseases that has affected …
dyslipidemia, insulin resistance, diabetes and cardiovascular diseases that has affected …
MiRNA-SARS-CoV-2 dialogue and prospective anti-COVID-19 therapies
COVID-19 is a highly transmissible disease caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), affects 226 countries and continents, and has resulted in> 6.2 …
coronavirus-2 (SARS-CoV-2), affects 226 countries and continents, and has resulted in> 6.2 …
Metabolic dysfunction and immunometabolism in COVID-19 pathophysiology and therapeutics
R Batabyal, N Freishtat, E Hill, M Rehman… - International Journal of …, 2021 - nature.com
The COVID-19 pandemic has emerged as a public health crisis and has placed a significant
burden on healthcare systems. Patients with underlying metabolic dysfunction, such as type …
burden on healthcare systems. Patients with underlying metabolic dysfunction, such as type …