Piperine (PIP) is an active alkaloid of black and long peppers. An increasing amount of
evidence is suggesting that PIP and its metabolite's could be a potential therapeutic to …

Alkamides refer to a class of natural active small-molecule products composed of fatty acids
and amine groups. These compounds are widely distributed in plants, and their unique …

Background Osteosarcoma is a primary bone malignancy associated with the highest
incidence rate. Chemotherapy for osteosarcoma has not substantially changed, and survival …

High doses of paracetamol (APAP) can cause irreversible liver damage. Piperine (P) inhibits
cytochrome P450, which is involved in the metabolism of various xenobiotics, including …

Oxidative injury is concerned with the pathogenesis of several liver injuries, including those
from acute liver failure to cirrhosis. This study was designed to explore the antioxidant …

Rationale Piperine, an alkaloid isolated from Piper nigrum L., has been demonstrated to
have many pharmacological effects and several health benefits. The aim of this work was to …

Piperine, an active plant alkaloid from black pepper (Piper nigrum), has several
pharmacological effects, namely antioxidant, anti-inflammatory and immunomodulatory …

In this article, we introduce a proof-of-concept strategy, Computational Predictive and
Electrochemical Detection of Metabolites (CP-EDM), to expedite the discovery of drug …

Guggulipid is known to be useful for hypercholesterolemia, arthritis, acne, and obesity.
These activities are attributed to its two principal isomeric active constituents, viz., E-and Z …