Polyphenols in plants: structure, biosynthesis, abiotic stress regulation, and practical applications

NV Zagoskina, MY Zubova, TL Nechaeva… - International Journal of …, 2023 - mdpi.com
Phenolic compounds or polyphenols are among the most common compounds of secondary
metabolism in plants. Their biosynthesis is characteristic of all plant cells and is carried out …

The impact of ellagitannins and their metabolites through gut microbiome on the gut health and brain wellness within the gut–brain axis

R Banc, ME Rusu, L Filip, DS Popa - Foods, 2023 - mdpi.com
Ellagitannins (ETs) are a large group of bioactive compounds found in plant-source foods,
such as pomegranates, berries, and nuts. The consumption of ETs has often been …

Therapeutic potential of polyphenols and other micronutrients of marine origin

L Pereira, J Cotas - Marine drugs, 2023 - mdpi.com
Polyphenols are compounds found in various plants and foods, known for their antioxidant
and anti-inflammatory properties. Recently, researchers have been exploring the therapeutic …

Phytochemicals and biological activities of walnut septum: A systematic review

L Mateș, ME Rusu, DS Popa - Antioxidants, 2023 - mdpi.com
In the last few decades, scientific evidence has stressed the importance of plants in the
prevention and/or supportive treatment of a plethora of diseases, many of them chronic, age …

Exploring the contribution of curcumin to cancer therapy: A systematic review of randomized controlled trials

C De Waure, C Bertola, G Baccarini, M Chiavarini… - Pharmaceutics, 2023 - mdpi.com
Although the anticancer role of curcumin has been extensively addressed in preclinical
research, only a few studies were carried out in humans, with conflicting results. The aim of …

Epigenetics-targeted drugs: current paradigms and future challenges

W Dai, X Qiao, Y Fang, R Guo, P Bai, S Liu… - … and Targeted Therapy, 2024 - nature.com
Epigenetics governs a chromatin state regulatory system through five key mechanisms: DNA
modification, histone modification, RNA modification, chromatin remodeling, and non-coding …

Sarcopenic obesity: involvement of oxidative stress and beneficial role of antioxidant flavonoids

UJ Jung - Antioxidants, 2023 - mdpi.com
Sarcopenic obesity, which refers to concurrent sarcopenia and obesity, is characterized by
decreased muscle mass, strength, and performance along with abnormally excessive fat …

What is the role of nutraceutical products in cancer patients? A systematic review of randomized clinical trials

R Di Napoli, N Balzano, A Mascolo, C Cimmino… - Nutrients, 2023 - mdpi.com
Chemotherapy represents the main pharmacological cancer treatment. Recently, positive
effects emerged with the combination of anticancer therapy and nutraceutical products. The …

A review on the composition, extraction and applications of phenolic compounds

GI Edo, SC Nwachukwu, ABM Ali, E Yousif, AN Jikah… - Ecological Frontiers, 2024 - Elsevier
The most common secondary metabolites of plants, phenolics are found throughout the
kingdom of plants. Plant polyphenols are receiving more and more attention because of their …

Unlocking the power of nanomedicine: the future of nutraceuticals in oncology treatment

M Singla, Smriti, S Gupta, P Behal, SK Singh… - Frontiers in …, 2023 - frontiersin.org
Cancer, an intricate and multifaceted disease, is characterized by the uncontrolled
proliferation of cells that can lead to serious health complications and ultimately death …