The role of miRNAs in liver diseases: Potential therapeutic and clinical applications
AS Doghish, MS Elballal, O Elazazy… - … -Research and Practice, 2023 - Elsevier
MicroRNAs (miRNAs) are a class of short, non-coding RNAs that function post-
transcriptionally to regulate gene expression by binding to particular mRNA targets and …
transcriptionally to regulate gene expression by binding to particular mRNA targets and …
[HTML][HTML] Cellular factors involved in the hepatitis C virus life cycle
HC Li, CH Yang, SY Lo - World Journal of Gastroenterology, 2021 - ncbi.nlm.nih.gov
The hepatitis C virus (HCV), an obligatory intracellular pathogen, highly depends on its host
cells to propagate successfully. The HCV life cycle can be simply divided into several stages …
cells to propagate successfully. The HCV life cycle can be simply divided into several stages …
Cardiac miR-19a/19b was induced and hijacked by CVB3 to facilitate virus replication via targeting viral genomic RdRp-encoding region
Y Wu, Y Yue, S Xiong - Antiviral Research, 2023 - Elsevier
Abstract Coxsackievirus B3 (CVB3) is one of the major pathogens of viral myocarditis,
lacking specific anti-virus therapeutic options. Increasing evidence has shown an important …
lacking specific anti-virus therapeutic options. Increasing evidence has shown an important …
MicroRNA expression profile of human umbilical vein endothelial cells in response to coxsackievirus A10 infection reveals a potential role of miR-143-3p in …
Y Hu, F Cui, S Wang, C Liu, S Zhang… - Frontiers in Cellular …, 2023 - frontiersin.org
Coxsackievirus A10 (CV-A10) has been one of the main etiologies of hand, foot, and mouth
disease (HFMD) epidemics in recent years and can cause mild to severe illness and even …
disease (HFMD) epidemics in recent years and can cause mild to severe illness and even …
MicroRNA-122 regulation of HCV infections: Insights from studies of miR-122-independent replication
Despite the advancement in antiviral therapy, Hepatitis C remains a global health challenge
and one of the leading causes of hepatitis related deaths worldwide. Hepatitis C virus, the …
and one of the leading causes of hepatitis related deaths worldwide. Hepatitis C virus, the …
Functional and clinical significance of dysregulated microRNAs in liver cancer
PS Huang, CJ Liao, YH Huang, CT Yeh, CY Chen… - Cancers, 2021 - mdpi.com
Simple Summary Liver cancer has a high mortality rate. Here, we retrospectively discuss the
current progress and dilemmas in the clinical research and treatment of liver cancer. We …
current progress and dilemmas in the clinical research and treatment of liver cancer. We …
Binding of microRNA-122 to the hepatitis C virus 5′ untranslated region modifies interactions with poly (C) binding protein 2 and the NS5B viral polymerase
S Scott, Y Li, O Bermek, JD Griffith… - Nucleic acids …, 2023 - academic.oup.com
Hepatitis C virus (HCV) requires two cellular factors, microRNA-122 (miR-122) and poly (C)
binding protein 2 (PCBP2), for optimal replication. These host factors compete for binding to …
binding protein 2 (PCBP2), for optimal replication. These host factors compete for binding to …
The relevance of MicroRNAs in the pathogenesis and prognosis of HCV-disease: The emergent role of miR-17-92 in cryoglobulinemic vasculitis
S Lorini, L Gragnani, AL Zignego - Viruses, 2020 - mdpi.com
Hepatitis C virus (HCV) is a major public health problem. HCV is a hepatotropic and
lymphotropic virus that leads to hepatocellular carcinoma (HCC) and lymphoproliferative …
lymphotropic virus that leads to hepatocellular carcinoma (HCC) and lymphoproliferative …
MicroRNA‐206 inhibits HCV proliferation through depressing ACC1 lipid synthesis signalling pathway
K Zheng, T Xia, N Liu, X Xia, Y Song… - Journal of Viral …, 2022 - Wiley Online Library
MicroRNAs are considered to play important roles in cell biological and pathological
progress. microRNA‐206 (miR‐206) was reported to participate in lipogenesis, and lipid …
progress. microRNA‐206 (miR‐206) was reported to participate in lipogenesis, and lipid …
Enhanced virus translation enables miR-122-independent Hepatitis C Virus propagation
ABSTRACT The 5′ untranslated region (UTR) of the hepatitis C virus (HCV) genome forms
RNA structures that regulate virus replication and translation. The region contains an …
RNA structures that regulate virus replication and translation. The region contains an …