The availability of long-acting injectable (LAI) antipsychotics for the treatment of
schizophrenia provides clinicians with options that deliver continuous drug exposure and …

Long acting injectables (LAI) have received increased research and commercial interest due
to their potential for improving treatment effectiveness and adherence for antipsychotic …

Oil depots are parenteral drug formulations meant for sustained release of lipophilic
compounds. Until now, a comprehensive understanding of the mechanism of drug …

This study was designed to investigate the effects of regular alcohol consumption on chronic
schizophrenic patients maintained on fluphenazine decanoate in the community. A group of …

Oil depots are parenteral drug formulations meant for sustained release of lipophilic
compounds. According to mass transport models, the drug-release rate from these injections …

The present pilot study introduces a method that might give novel insights in drug absorption
processes from intramuscularly administered depots. An oily suspension or an aqueous …

Long-term therapy of nandrolone (N) is recommended to increase mineral density and
muscle strength. Using a parenteral sustained release drug formulation with nandrolone …

We assume that the reader is familiar with antipsychotic maintenance treatment, as well as
some of the current practice guidelines for LAI use. 1-3 Such practice is often misguided in …

Understanding how the biological environment contributes to drug release following
administration is increasingly becoming a focus for drug delivery research. Achieving …

There is an urgent need for in vitro dissolution test setups for intramuscularly applied dosage
forms. Especially biorelevant methods are needed to predict the in vivo behavior of newly …