[HTML][HTML] Development and challenges of antimicrobial peptides for therapeutic applications
More than 3000 antimicrobial peptides (AMPs) have been discovered, seven of which have
been approved by the US Food and Drug Administration (FDA). Now commercialized, these …
been approved by the US Food and Drug Administration (FDA). Now commercialized, these …
An introduction to B‐cell epitope mapping and in silico epitope prediction
L Potocnakova, M Bhide… - Journal of immunology …, 2016 - Wiley Online Library
Identification of B‐cell epitopes is a fundamental step for development of epitope‐based
vaccines, therapeutic antibodies, and diagnostic tools. Epitope‐based antibodies are …
vaccines, therapeutic antibodies, and diagnostic tools. Epitope‐based antibodies are …
AllergenFP: allergenicity prediction by descriptor fingerprints
Motivation: Allergenicity, like antigenicity and immunogenicity, is a property encoded linearly
and non-linearly, and therefore the alignment-based approaches are not able to identify this …
and non-linearly, and therefore the alignment-based approaches are not able to identify this …
Genetically modified foods: safety, risks and public concerns—a review
AS Bawa, KR Anilakumar - Journal of food science and technology, 2013 - Springer
Genetic modification is a special set of gene technology that alters the genetic machinery of
such living organisms as animals, plants or microorganisms. Combining genes from different …
such living organisms as animals, plants or microorganisms. Combining genes from different …
[HTML][HTML] AllerTOP - a server for in silico prediction of allergens
I Dimitrov, DR Flower, I Doytchinova - BMC bioinformatics, 2013 - Springer
Background Allergy is a form of hypersensitivity to normally innocuous substances, such as
dust, pollen, foods or drugs. Allergens are small antigens that commonly provoke an IgE …
dust, pollen, foods or drugs. Allergens are small antigens that commonly provoke an IgE …
Prediction of continuous B‐cell epitopes in an antigen using recurrent neural network
S Saha, GPS Raghava - Proteins: Structure, Function, and …, 2006 - Wiley Online Library
B‐cell epitopes play a vital role in the development of peptide vaccines, in diagnosis of
diseases, and also for allergy research. Experimental methods used for characterizing …
diseases, and also for allergy research. Experimental methods used for characterizing …
AlgPred: prediction of allergenic proteins and mapping of IgE epitopes
S Saha, GPS Raghava - Nucleic acids research, 2006 - academic.oup.com
In this study a systematic attempt has been made to integrate various approaches in order to
predict allergenic proteins with high accuracy. The dataset used for testing and training …
predict allergenic proteins with high accuracy. The dataset used for testing and training …
AllerCatPro—prediction of protein allergenicity potential from the protein sequence
S Maurer-Stroh, NL Krutz, PS Kern, V Gunalan… - …, 2019 - academic.oup.com
Motivation Due to the risk of inducing an immediate Type I (IgE-mediated) allergic response,
proteins intended for use in consumer products must be investigated for their allergenic …
proteins intended for use in consumer products must be investigated for their allergenic …
Phage-display immunoprecipitation sequencing of the antibody epitope repertoire in inflammatory bowel disease reveals distinct antibody signatures
Inflammatory bowel diseases (IBDs), eg, Crohn's disease (CD) and ulcerative colitis (UC),
are chronic immune-mediated inflammatory diseases. A comprehensive overview of an IBD …
are chronic immune-mediated inflammatory diseases. A comprehensive overview of an IBD …
Allergic cross‐reactivity: from gene to the clinic
F Ferreira, T Hawranek, P Gruber, N Wopfner, A Mari - Allergy, 2004 - Wiley Online Library
A large number of allergenic proteins have now their complete cDNA sequences determined
and in some cases also the 3D structures. It turned out that most allergens could be grouped …
and in some cases also the 3D structures. It turned out that most allergens could be grouped …