[HTML][HTML] Development and challenges of antimicrobial peptides for therapeutic applications

CH Chen, TK Lu - Antibiotics, 2020 - mdpi.com
More than 3000 antimicrobial peptides (AMPs) have been discovered, seven of which have
been approved by the US Food and Drug Administration (FDA). Now commercialized, these …

An introduction to B‐cell epitope mapping and in silico epitope prediction

L Potocnakova, M Bhide… - Journal of immunology …, 2016 - Wiley Online Library
Identification of B‐cell epitopes is a fundamental step for development of epitope‐based
vaccines, therapeutic antibodies, and diagnostic tools. Epitope‐based antibodies are …

AllergenFP: allergenicity prediction by descriptor fingerprints

I Dimitrov, L Naneva, I Doytchinova, I Bangov - Bioinformatics, 2014 - academic.oup.com
Motivation: Allergenicity, like antigenicity and immunogenicity, is a property encoded linearly
and non-linearly, and therefore the alignment-based approaches are not able to identify this …

Genetically modified foods: safety, risks and public concerns—a review

AS Bawa, KR Anilakumar - Journal of food science and technology, 2013 - Springer
Genetic modification is a special set of gene technology that alters the genetic machinery of
such living organisms as animals, plants or microorganisms. Combining genes from different …

[HTML][HTML] AllerTOP - a server for in silico prediction of allergens

I Dimitrov, DR Flower, I Doytchinova - BMC bioinformatics, 2013 - Springer
Background Allergy is a form of hypersensitivity to normally innocuous substances, such as
dust, pollen, foods or drugs. Allergens are small antigens that commonly provoke an IgE …

Prediction of continuous B‐cell epitopes in an antigen using recurrent neural network

S Saha, GPS Raghava - Proteins: Structure, Function, and …, 2006 - Wiley Online Library
B‐cell epitopes play a vital role in the development of peptide vaccines, in diagnosis of
diseases, and also for allergy research. Experimental methods used for characterizing …

AlgPred: prediction of allergenic proteins and mapping of IgE epitopes

S Saha, GPS Raghava - Nucleic acids research, 2006 - academic.oup.com
In this study a systematic attempt has been made to integrate various approaches in order to
predict allergenic proteins with high accuracy. The dataset used for testing and training …

AllerCatPro—prediction of protein allergenicity potential from the protein sequence

S Maurer-Stroh, NL Krutz, PS Kern, V Gunalan… - …, 2019 - academic.oup.com
Motivation Due to the risk of inducing an immediate Type I (IgE-mediated) allergic response,
proteins intended for use in consumer products must be investigated for their allergenic …

Phage-display immunoprecipitation sequencing of the antibody epitope repertoire in inflammatory bowel disease reveals distinct antibody signatures

AR Bourgonje, S Andreu-Sánchez, T Vogl, S Hu… - Immunity, 2023 - cell.com
Inflammatory bowel diseases (IBDs), eg, Crohn's disease (CD) and ulcerative colitis (UC),
are chronic immune-mediated inflammatory diseases. A comprehensive overview of an IBD …

Allergic cross‐reactivity: from gene to the clinic

F Ferreira, T Hawranek, P Gruber, N Wopfner, A Mari - Allergy, 2004 - Wiley Online Library
A large number of allergenic proteins have now their complete cDNA sequences determined
and in some cases also the 3D structures. It turned out that most allergens could be grouped …