Medaka—a model organism from the far East

J Wittbrodt, A Shima, M Schartl - Nature Reviews Genetics, 2002 - nature.com
Genome sequencing has yielded a plethora of new genes the function of which can be
unravelled through comparative genomic approaches. Increasingly, developmental …

Medakafish as a model system for vertebrate developmental genetics

Y Ishikawa - Bioessays, 2000 - Wiley Online Library
Several teleosts, such as the zebrafish and the medakafish or medaka (Oryzias latipes), are
used as vertebrate model systems in various fields of biology. The medaka is suitable for …

Establishment of a normal medakafish spermatogonial cell line capable of sperm production in vitro

Y Hong, T Liu, H Zhao, H Xu, W Wang… - Proceedings of the …, 2004 - National Acad Sciences
Spermatogonia are the male germ stem cells that continuously produce sperm for the next
generation. Spermatogenesis is a complicated process that proceeds through mitotic phase …

Generation of medaka fish haploid embryonic stem cells

M Yi, N Hong, Y Hong - Science, 2009 - science.org
Haploid embryonic stem (ES) cells combine haploidy and pluripotency, enabling direct
genetic analyses of recessive phenotypes in vertebrate cells. Haploid cells have been …

The Oct4 homologue PouV and Nanog regulate pluripotency in chicken embryonic stem cells

F Lavial, H Acloque, F Bertocchini, DJ MacLeod… - 2007 - journals.biologists.com
Embryonic stem cells (ESC) have been isolated from pregastrulation mammalian embryos.
The maintenance of their pluripotency and ability to self-renew has been shown to be …

The Genomic and Genetic Toolbox of the Teleost Medaka (Oryzias latipes)

S Kirchmaier, K Naruse, J Wittbrodt, F Loosli - Genetics, 2015 - academic.oup.com
Abstract The Japanese medaka, Oryzias latipes, is a vertebrate teleost model with a long
history of genetic research. A number of unique features and established resources …

[HTML][HTML] Medaka as a research organism: past, present and future

A Shima, H Mitani - Mechanisms of development, 2004 - Elsevier
This introductory review briefly describes the history of medaka as a research organism and
the previous accomplishments of the medaka field. The medaka genome project currently …

Production of zebrafish germ-line chimeras from embryo cell cultures

C Ma, L Fan, R Ganassin, N Bols… - Proceedings of the …, 2001 - National Acad Sciences
Although the zebrafish possesses many characteristics that make it a valuable model for
genetic studies of vertebrate development, one deficiency of this model system is the …

Asian medaka fishes offer new models for studying mechanisms of seawater adaptation

K Inoue, Y Takei - Comparative Biochemistry and Physiology Part B …, 2003 - Elsevier
Japanese medaka (Oryzias latipes) is a freshwater (FW) teleost that is popular throughout
the world for laboratory use. In this paper, we discuss the utility of Japanese medaka and …

[HTML][HTML] Medaka vasa is required for migration but not survival of primordial germ cells

M Li, N Hong, H Xu, M Yi, C Li, J Gui, Y Hong - Mechanisms of …, 2009 - Elsevier
vasa is essential for germline development. However, the precise processes in which vasa
involves vary considerably in diverse animal phyla. Here we show that vasa is required for …