Naturalizing mouse models for immunology
AL Graham - Nature Immunology, 2021 - nature.com
Laboratory mice have provided invaluable insight into mammalian immune systems. Yet the
immune phenotypes of mice bred and maintained in conventional laboratory conditions …
immune phenotypes of mice bred and maintained in conventional laboratory conditions …
Macroimmunology: The drivers and consequences of spatial patterns in wildlife immune defence
The prevalence and intensity of parasites in wild hosts varies across space and is a key
determinant of infection risk in humans, domestic animals and threatened wildlife. Because …
determinant of infection risk in humans, domestic animals and threatened wildlife. Because …
Land use-induced spillover: a call to action to safeguard environmental, animal, and human health
RK Plowright, JK Reaser, H Locke… - The Lancet Planetary …, 2021 - thelancet.com
The rapid global spread and human health impacts of SARS-CoV-2, the virus that causes
COVID-19, show humanity's vulnerability to zoonotic disease pandemics. Although …
COVID-19, show humanity's vulnerability to zoonotic disease pandemics. Although …
Normalizing the environment recapitulates adult human immune traits in laboratory mice
Our current understanding of immunology was largely defined in laboratory mice, partly
because they are inbred and genetically homogeneous, can be genetically manipulated …
because they are inbred and genetically homogeneous, can be genetically manipulated …
Interactions between multiple helminths and the gut microbiota in wild rodents
J Kreisinger, G Bastien, HC Hauffe… - … of the Royal …, 2015 - royalsocietypublishing.org
The gut microbiota is vital to host health and, as such, it is important to elucidate the
mechanisms altering its composition and diversity. Intestinal helminths are host …
mechanisms altering its composition and diversity. Intestinal helminths are host …
Sexual dimorphism in immunity across animals: a meta‐analysis
In animals, sex differences in immunity are proposed to shape variation in infection
prevalence and intensity among individuals in a population, with females typically expected …
prevalence and intensity among individuals in a population, with females typically expected …
The gut microbiome of laboratory mice: considerations and best practices for translational research
AC Ericsson, CL Franklin - Mammalian Genome, 2021 - Springer
Just as the gut microbiota (GM) is now recognized as an integral mediator of environmental
influences on human physiology, susceptibility to disease, and response to pharmacological …
influences on human physiology, susceptibility to disease, and response to pharmacological …
A review of non-invasive sampling in wildlife disease and health research: what's new?
AK Schilling, MV Mazzamuto, C Romeo - Animals, 2022 - mdpi.com
Simple Summary The interest in wildlife research has increased in the last decades as more
scientists work within a One Health framework that regards human, livestock and wildlife …
scientists work within a One Health framework that regards human, livestock and wildlife …
The conservation physiology toolbox: status and opportunities
For over a century, physiological tools and techniques have been allowing researchers to
characterize how organisms respond to changes in their natural environment and how they …
characterize how organisms respond to changes in their natural environment and how they …
Ecophysiology meets conservation: understanding the role of disease in amphibian population declines
AR Blaustein, SS Gervasi… - … of the Royal …, 2012 - royalsocietypublishing.org
Infectious diseases are intimately associated with the dynamics of biodiversity. However, the
role that infectious disease plays within ecological communities is complex. The complex …
role that infectious disease plays within ecological communities is complex. The complex …