For many years, antimuscarinic drugs have been the first-line pharmacological treatment for
urgency, frequency, and urge incontinence, all symptoms of the disorder termed overactive …

Contraction of the bladder, voluntary or involuntary, involves stimulation of the muscarinic
receptors on the detrusor by acetylcholine, released from activated cholinergic nerves …

Objective: Despite the various treatment and prevention options for catheter-related bladder
discomfort (CRBD), many uncertainties persist in clinical practice. To systematically review …

Myogenic activity, distention of the detrusor, and signals from the urothelium may initiate
voiding. In the bladder, afferent nerves have been identified not only in the detrusor, but also …

Purpose: Overactive bladder is common in the elderly population, which is susceptible to
cognitive disorders and drug induced cognitive impairment. Existing overactive bladder …

Background: The complex relationship between bladder and bowel function has
implications for treating pelvic disorders. In this systematic review, we discuss the …

Background. Intraoperative urinary catheterization might cause postoperative catheter
related bladder discomfort (CRBD). We evaluated the efficacy of ketamine as a treatment …

Objective Overactive bladder (OAB) is a particular challenge to treat in older adults with co-
morbid conditions taking multiple medications. Antimuscarinics (eg, solifenacin …

The urethral catheter is used in various clinical situations such as diagnosing urologic
disease, urine drainage in patients after surgery, and for patients who cannot urinate …

Background Bladder discomfort related to an indwelling catheter can exacerbate
postoperative pain. It mimics overactive bladder syndrome that is resistant to conventional …