Background Rosmarinic acid (RA) is widely distributed in plant species of Lamiaceae and
Boraginaceae families, among others. Structurally RA is an ester of caffeic acid and 3, 4 …

Hairy root (HR) culture, a successful biotechnology combining in vitro tissue culture with
recombinant DNA machinery, is intended for the genetic improvement of plants. This …

Rosmarinic acid (RA) is a highly valued natural phenolic compound that is very commonly
found in plants of the families Lamiaceae and Boraginaceae, including Coleus blumei …

Modern lifestyle factors, such as physical inactivity, obesity, smoking, and exposure to
environmental pollution, induce excessive generation of free radicals and reactive oxygen …

BACKGROUND Dracocephalum kotschyi Boiss. is a valuable source of rosmarinic acid (RA)
and methoxylated hydroxyflavones (such as xanthomicrol and cirsimaritin) with antioxidative …

Dracocephalum kotschyi Boiss. is one of the important threatened traditional species of
medicinal herbs; last pharmaceutical research has shown that rosmarinic acid (RA) and …

Objectives. Dracocephalum has over 60 species and is found mainly in the temperate
regions of Asia and Europe. One of these species, ie, Dracocephalum kotschyi Boiss, is …

BACKGROUND A wide variety of secondary metabolites are synthesized from primary
metabolites by plants which have a vast range in pharmaceutical, food additive and …

Background: Plant biofactories are biotechnological platforms based on plant cell and organ
cultures used for the production of pharmaceuticals and biopharmaceuticals, although to …

In this work, Isatis tinctoria hairy root cultures (ITHRCs) were established as an alternative
source for flavonoids (FL) production. I. tinctoria hairy root line V was found to be the most …