Left ventricular assist devices (LVAD) have revolutionized the management of advanced
heart failure. However, complications rates remain high, among which hemorrhagic and …

While earlier studies reported no relevant effect of the HeartMate 3 (HM3) artificial pulse
(AP) on bulk pump washout, its effect on regions with prolonged residence times remains …

Purpose To develop a mathematical model for predicting shear-induced von Willebrand
factor (vWF) function modification which can be used to guide ventricular assist devices …

Purpose The objective of this study is to develop a bleeding risk model for assessing device-
induced bleeding risk in patients supported with blood contact medical devices (BCMDs) …

This study aims to develop simulation methods, performance evaluation methods, and
optimization strategies for blood pumps. Computational fluid dynamics, in-vitro …

The loss of high molecular weight multimers (HMWM) of von Willebrand factor (vWF) in
aortic stenosis (AS) and continuous-flow left ventricular assist devices (cf-LVADs) is believed …

The configuration of proteins is critical for their biochemical behavior. Mechanical stresses
that act on them can affect their behavior leading to the development of decease. The von …

Nonsurgical bleeding is the most frequent complication of left ventricular assist device
(LVAD) support. Supraphysiologic shear rates generated in LVAD causes impaired platelet …

To investigate the effects of blood pumps operated in different modes on nonphysiologic
flow patterns, cell and protein function, and the risk of bleeding, thrombosis, and hemolysis …

Purpose This study aimed to investigate the effects of lower-extremity cannulation on the
intra-arterial hemodynamic environment, oxygen content, blood damage, and thrombosis …