[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: Current status and future perspectives

H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

[PDF][PDF] Vascular endothelial growth factor (VEGF)-key factor in normal and pathological angiogenesis

CS Melincovici, AB Boşca, S Şuşman… - Rom J Morphol …, 2018 - rjme.ro
Vascular endothelial growth factor (VEGF) represents a growth factor with important pro-
angiogenic activity, having a mitogenic and an anti-apoptotic effect on endothelial cells …

Ten years of anti-vascular endothelial growth factor therapy

N Ferrara, AP Adamis - Nature reviews Drug discovery, 2016 - nature.com
The targeting of vascular endothelial growth factor A (VEGFA), a crucial regulator of both
normal and pathological angiogenesis, has revealed innovative therapeutic approaches in …

Vascular endothelial growth factor signaling in development and disease

S Karaman, VM Leppänen, K Alitalo - Development, 2018 - journals.biologists.com
Vascular endothelial growth factors (VEGFs) are best known for their involvement in
orchestrating the development and maintenance of the blood and lymphatic vascular …

[HTML][HTML] Immune reactions after modern lamellar (DALK, DSAEK, DMEK) versus conventional penetrating corneal transplantation

D Hos, M Matthaei, F Bock, K Maruyama… - Progress in retinal and …, 2019 - Elsevier
In the past decade, novel lamellar keratoplasty techniques such as Deep Anterior Lamellar
Keratoplasty (DALK) for anterior keratoplasty and Descemet stripping automated endothelial …

Risk factors and biomarkers of age-related macular degeneration

NG Lambert, H ElShelmani, MK Singh… - Progress in retinal and …, 2016 - Elsevier
A biomarker can be a substance or structure measured in body parts, fluids or products that
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …

Synthesis, properties and biomedical applications of hydrolytically degradable materials based on aliphatic polyesters and polycarbonates

RP Brannigan, AP Dove - Biomaterials science, 2017 - pubs.rsc.org
Polyester-based polymers represent excellent candidates in synthetic biodegradable and
bioabsorbable materials for medical applications owing to their tailorable properties. The …

Vascular endothelial growth factor (VEGF) and its receptor (VEGFR) signaling in angiogenesis: a crucial target for anti-and pro-angiogenic therapies

M Shibuya - Genes & cancer, 2011 - journals.sagepub.com
The vascular endothelial growth factor (VEGF) and its receptor (VEGFR) have been shown
to play major roles not only in physiological but also in most pathological angiogenesis …

Vascular endothelial growth factor and its receptor system: physiological functions in angiogenesis and pathological roles in various diseases

M Shibuya - The Journal of Biochemistry, 2013 - academic.oup.com
Vascular endothelial growth factors (VEGFs) belong to the platelet-derived growth factor
supergene family, and they play central roles in the regulation of angiogenesis and …

Signal transduction by vascular endothelial growth factor receptors

S Koch, L Claesson-Welsh - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Vascular endothelial growth factors (VEGFs) are master regulators of vascular development
and of blood and lymphatic vessel function during health and disease in the adult. It is …