Fueled by aging populations and continued environmental contamination, the global burden
of Parkinson's disease (PD) is increasing. The disease, or more appropriately diseases …

Crocin is a hydrophilic carotenoid that is synthesized in the flowers of the Crocus genus.
Numerous in vitro and in vivo research projects have been published about the biological …

Background Clinical research in natural product-based psychopharmacology has revealed
a variety of promising herbal medicines that may provide benefit in the treatment of mild …

Ethnopharmacological relevance Xianglian pill (XLP), a traditional Chinese formula, is
widely used as treatment for ulcerative colitis (UC) in China. However, the mechanism of its …

The main constituents of saffron are the apocarotenoids crocins and crocetin, present in the
stigmas. Numerous healthy properties, especially those related to the effects on the central …

Saffron (Crocus sativus L.) is a spice used worldwide as a colouring and flavouring agent.
Saffron is also a source of multiple bioactive constituents with potential health benefits …

The recovery of physiologically bioactive ingredients from agricultural wastes as an
abundant and low-cost source for the production of high value-added mutraceuticlas has …

Orally administered crocin rapidly and efficiently rescues depressive-like behaviors in
depression models; however, crocin levels in the circulatory and central nervous systems …

Adverse reactions to azathioprine (AZA) vary greatly among individuals, which is associated
with the variable levels of its major metabolites 6-thioguanine nucleotides (6-TGN) and 6 …

The therapeutic effects of saffron have been reported and described in relation to its major
derivatives. Among them, in terms of saffron's properties, crocin and crocetin absorption and …